Investigating the structure of the DENV-2 envelope protein in complex with the EDE2 B7 antibody using metadynamics simulations
Dengue is a serious disease with a particularly high transmission rate in the tropics. There is currently only one WHO-approved vaccine, but it has limitations. A key therapeutic target on the dengue virus is the envelope glycoprotein (E protein) dimer which coats the outer surface. A new type of...
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Format: | Final Year Project (FYP) |
Language: | English |
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2016
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Online Access: | http://hdl.handle.net/10356/69194 |