Theoretical study of the binding of BH3 peptides to BCL-2 proteins towards a novel anticancer strategy
BCL-2 proteins play a significant role in regulating apoptosis through complex interactions between antiapoptotic and apoptotic members. In cancer cells, the overexpression of antiapoptotic proteins inhibit the heterodimerization of apoptotic proteins, preventing cell death. Hence, through studies f...
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| Format: | Thesis |
| Language: | English |
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2017
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| Online Access: | http://hdl.handle.net/10356/70895 |