Raman Monte Carlo simulation for light propagation in tissue with embedded object

Monte Carlo (MC) stimulation is one of the prominent simulation technique and is rapidly becoming the model of choice to study light-tissue interaction. Monte Carlo simulation for light transport in multi-layered tissue (MCML) is adapted and modelled with different geometry by integrating embedde...

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Bibliographic Details
Main Author: Humaira Jaafar
Other Authors: Manojit Pramanik
Format: Final Year Project (FYP)
Language:English
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/10356/71974
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author Humaira Jaafar
author2 Manojit Pramanik
author_facet Manojit Pramanik
Humaira Jaafar
author_sort Humaira Jaafar
collection NTU
description Monte Carlo (MC) stimulation is one of the prominent simulation technique and is rapidly becoming the model of choice to study light-tissue interaction. Monte Carlo simulation for light transport in multi-layered tissue (MCML) is adapted and modelled with different geometry by integrating embedded objects of various shapes (i.e. sphere, cylinder, cuboid and ellipsoid) into the multi-layered structure. These geometries would be useful in providing a realistic tissue structure such as modelling for tumors, lymph nodes, head, blood vessels and other human body parts. In this context, the project deals with several MC simulations performed on various geometric medium and optical properties of a tissue. Stimulation of MCML with embedded object (MCML-EO) was improvised in which propagation of the photon in the defined medium was able to handle Raman scattering. Simulations were experimented on a modeled breast tissue with tumor by initializing tissue’s optical properties and were subjected to varying inputs of number of photons and probability. Simulation results records information such as diffused reflectance, diffused transmittance and absorbance. Moreover, results were presented in both A-line and B-line scans for embedded objects in order to determine spatial location where Raman photons were generated and predictions about the effect of tissue geometry.
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spelling ntu-10356/719742023-03-03T15:31:57Z Raman Monte Carlo simulation for light propagation in tissue with embedded object Humaira Jaafar Manojit Pramanik School of Chemical and Biomedical Engineering DRNTU::Engineering::Bioengineering Monte Carlo (MC) stimulation is one of the prominent simulation technique and is rapidly becoming the model of choice to study light-tissue interaction. Monte Carlo simulation for light transport in multi-layered tissue (MCML) is adapted and modelled with different geometry by integrating embedded objects of various shapes (i.e. sphere, cylinder, cuboid and ellipsoid) into the multi-layered structure. These geometries would be useful in providing a realistic tissue structure such as modelling for tumors, lymph nodes, head, blood vessels and other human body parts. In this context, the project deals with several MC simulations performed on various geometric medium and optical properties of a tissue. Stimulation of MCML with embedded object (MCML-EO) was improvised in which propagation of the photon in the defined medium was able to handle Raman scattering. Simulations were experimented on a modeled breast tissue with tumor by initializing tissue’s optical properties and were subjected to varying inputs of number of photons and probability. Simulation results records information such as diffused reflectance, diffused transmittance and absorbance. Moreover, results were presented in both A-line and B-line scans for embedded objects in order to determine spatial location where Raman photons were generated and predictions about the effect of tissue geometry. Bachelor of Engineering (Chemical and Biomolecular Engineering) 2017-05-23T06:16:30Z 2017-05-23T06:16:30Z 2017 Final Year Project (FYP) http://hdl.handle.net/10356/71974 en Nanyang Technological University 39 p. application/pdf
spellingShingle DRNTU::Engineering::Bioengineering
Humaira Jaafar
Raman Monte Carlo simulation for light propagation in tissue with embedded object
title Raman Monte Carlo simulation for light propagation in tissue with embedded object
title_full Raman Monte Carlo simulation for light propagation in tissue with embedded object
title_fullStr Raman Monte Carlo simulation for light propagation in tissue with embedded object
title_full_unstemmed Raman Monte Carlo simulation for light propagation in tissue with embedded object
title_short Raman Monte Carlo simulation for light propagation in tissue with embedded object
title_sort raman monte carlo simulation for light propagation in tissue with embedded object
topic DRNTU::Engineering::Bioengineering
url http://hdl.handle.net/10356/71974
work_keys_str_mv AT humairajaafar ramanmontecarlosimulationforlightpropagationintissuewithembeddedobject