Lysosomal interplay between ubiquitination and phosphorylation regulates chaperone-mediated autophagy
Chaperone-mediated autophagy (CMA) is a selective autophagic pathway that degrades soluble cytosolic proteins. It utilizes a cascade of chaperones and co-chaperones to recognize and deliver the substrates to the lysosome for degradation. Basal CMA operates in all mammalian cells in order to maintain...
मुख्य लेखक: | |
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अन्य लेखक: | |
स्वरूप: | थीसिस |
भाषा: | English |
प्रकाशित: |
2017
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विषय: | |
ऑनलाइन पहुंच: | http://hdl.handle.net/10356/72725 |