An early role for zebrafish hoxd4a and its cofactors in hematopoiesis

In contrast to a more expected role of Hox genes during gastrulation, knockdown of hoxd4a results in decreased expression of the hemangioblast maker scl and subsequent defects in hematopoiesis. To confirm an early role for hoxd4a, we engineered inducible Hoxd4a activity by fusion to the ligand bindi...

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Bibliographic Details
Main Author: Zhang, Changqing
Other Authors: Mark Featherstone
Format: Thesis
Language:English
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/10356/73069

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