The role of KMT2A in zebrafish development

The Histone-lysine N-methyltransferase2A (KMT2A) acts as a global regulator of gene expression. KMT2A is responsible for methylation of lysine 4 of histone 3 (H3K4) on a small subset of genes, including HOX genes. The methylation of H3K4 neutralizes lysine positive charge thus making associated gene...

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Bibliographic Details
Main Author: Anastasiia, Fadieieva
Other Authors: Mark Featherstone
Format: Thesis
Language:English
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10356/73275