Investigating the role of kindlin-3 in protein translation and tumorigenesis via interaction with RACK1
Kindlins are a family of three FERM-containing cytoplasmic proteins that are expressed in various cell types. Kindlins modulate cell-cell and cell-Extracellular Matrix (ECM) interaction by regulating the ligand-binding affinity and avidity of the cell surface adhesion molecules-integrins. Kindlin-3...
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| Format: | Thesis |
| Language: | English |
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2018
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| Online Access: | http://hdl.handle.net/10356/73451 |