Programming of an Arduino control unit for Cell Culture Incubation Chamber
Today, the problems faced by researchers include the cost associated with recalls of drugs which have side effects went undetected and lacked effective and low-cost model systems to analyse them further. Three-dimensional (3D) tissue models offer more effective and robust pre-clinical screening as c...
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| Other Authors: | |
| Format: | Final Year Project (FYP) |
| Language: | English |
| Published: |
2018
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| Online Access: | http://hdl.handle.net/10356/75185 |
| _version_ | 1811686619258814464 |
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| author | Lim, Ding Yan |
| author2 | Pui Tze Sian |
| author_facet | Pui Tze Sian Lim, Ding Yan |
| author_sort | Lim, Ding Yan |
| collection | NTU |
| description | Today, the problems faced by researchers include the cost associated with recalls of drugs which have side effects went undetected and lacked effective and low-cost model systems to analyse them further. Three-dimensional (3D) tissue models offer more effective and robust pre-clinical screening as compared to two-dimensional (2D) tissue models which are relatively lower in cost and shorter time to cultivate. Devices currently available on the market are not able to handle drug perfusion at cell-viable conditions for long-term testing and imaging experiments at a lower cost. This paper suggests building a portable microcontroller to integrate with portable incubator enclosure for cell experiments and drug screening of three-dimensional (3D) tissue models, presenting a useful diagnostic tool for screening cost-effectively. The portable microcontroller must be able to regulate consistent environment for cell experiments to perform long-term testing and imaging without any disruption to cell viability. |
| first_indexed | 2024-10-01T05:03:18Z |
| format | Final Year Project (FYP) |
| id | ntu-10356/75185 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:03:18Z |
| publishDate | 2018 |
| record_format | dspace |
| spelling | ntu-10356/751852023-03-03T15:35:45Z Programming of an Arduino control unit for Cell Culture Incubation Chamber Lim, Ding Yan Pui Tze Sian School of Chemical and Biomedical Engineering DRNTU::Engineering::Bioengineering Today, the problems faced by researchers include the cost associated with recalls of drugs which have side effects went undetected and lacked effective and low-cost model systems to analyse them further. Three-dimensional (3D) tissue models offer more effective and robust pre-clinical screening as compared to two-dimensional (2D) tissue models which are relatively lower in cost and shorter time to cultivate. Devices currently available on the market are not able to handle drug perfusion at cell-viable conditions for long-term testing and imaging experiments at a lower cost. This paper suggests building a portable microcontroller to integrate with portable incubator enclosure for cell experiments and drug screening of three-dimensional (3D) tissue models, presenting a useful diagnostic tool for screening cost-effectively. The portable microcontroller must be able to regulate consistent environment for cell experiments to perform long-term testing and imaging without any disruption to cell viability. Bachelor of Engineering (Chemical and Biomolecular Engineering) 2018-05-30T01:33:28Z 2018-05-30T01:33:28Z 2018 Final Year Project (FYP) http://hdl.handle.net/10356/75185 en Nanyang Technological University 58 p. application/pdf |
| spellingShingle | DRNTU::Engineering::Bioengineering Lim, Ding Yan Programming of an Arduino control unit for Cell Culture Incubation Chamber |
| title | Programming of an Arduino control unit for Cell Culture Incubation Chamber |
| title_full | Programming of an Arduino control unit for Cell Culture Incubation Chamber |
| title_fullStr | Programming of an Arduino control unit for Cell Culture Incubation Chamber |
| title_full_unstemmed | Programming of an Arduino control unit for Cell Culture Incubation Chamber |
| title_short | Programming of an Arduino control unit for Cell Culture Incubation Chamber |
| title_sort | programming of an arduino control unit for cell culture incubation chamber |
| topic | DRNTU::Engineering::Bioengineering |
| url | http://hdl.handle.net/10356/75185 |
| work_keys_str_mv | AT limdingyan programmingofanarduinocontrolunitforcellcultureincubationchamber |