Tissue imaging using nonlinear laser scanning microscope
The importance for a fast and efficient imaging technique is essential today for imaging of biological tissues. From retinal diseases and disorders such as Retinal Vein Occlusion, Diabetic Retinopathy, and Retinal Tear or Detachments to cancer research in the liver, there are sophisticated technolog...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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2018
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| Online Access: | http://hdl.handle.net/10356/75631 |
| _version_ | 1811685018592870400 |
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| author | Tay, Kenneth ZiHan |
| author2 | Liu Quan |
| author_facet | Liu Quan Tay, Kenneth ZiHan |
| author_sort | Tay, Kenneth ZiHan |
| collection | NTU |
| description | The importance for a fast and efficient imaging technique is essential today for imaging of biological tissues. From retinal diseases and disorders such as Retinal Vein Occlusion, Diabetic Retinopathy, and Retinal Tear or Detachments to cancer research in the liver, there are sophisticated technologies available today to diagnose these diseases on a macroscopic level, but the optimum parameters aren’t pre-determined prior to the imaging of these biological tissues. A novel technology called two-photon microscopy, which is based on the principle of Confocal Laser Scanning Microscopy and Two-Photon Excitation is being explored for its application in imaging the microstructures of the retina in vivo. This project thus aims to determine the optimal parameters in the imaging of biological tissues using the principles of Confocal Laser Scanning Microscopy to carry out ex-vivo Two-Photon Microscopy. Ultimately obtaining successful images to observe and understand the microstructures of biological tissues such as the retina. |
| first_indexed | 2024-10-01T04:37:51Z |
| format | Final Year Project (FYP) |
| id | ntu-10356/75631 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T04:37:51Z |
| publishDate | 2018 |
| record_format | dspace |
| spelling | ntu-10356/756312023-03-03T15:35:14Z Tissue imaging using nonlinear laser scanning microscope Tay, Kenneth ZiHan Liu Quan School of Chemical and Biomedical Engineering DRNTU::Science::Physics::Optics and light The importance for a fast and efficient imaging technique is essential today for imaging of biological tissues. From retinal diseases and disorders such as Retinal Vein Occlusion, Diabetic Retinopathy, and Retinal Tear or Detachments to cancer research in the liver, there are sophisticated technologies available today to diagnose these diseases on a macroscopic level, but the optimum parameters aren’t pre-determined prior to the imaging of these biological tissues. A novel technology called two-photon microscopy, which is based on the principle of Confocal Laser Scanning Microscopy and Two-Photon Excitation is being explored for its application in imaging the microstructures of the retina in vivo. This project thus aims to determine the optimal parameters in the imaging of biological tissues using the principles of Confocal Laser Scanning Microscopy to carry out ex-vivo Two-Photon Microscopy. Ultimately obtaining successful images to observe and understand the microstructures of biological tissues such as the retina. Bachelor of Engineering (Chemical and Biomolecular Engineering) 2018-06-05T09:20:01Z 2018-06-05T09:20:01Z 2018 Final Year Project (FYP) http://hdl.handle.net/10356/75631 en Nanyang Technological University 51 p. application/pdf |
| spellingShingle | DRNTU::Science::Physics::Optics and light Tay, Kenneth ZiHan Tissue imaging using nonlinear laser scanning microscope |
| title | Tissue imaging using nonlinear laser scanning microscope |
| title_full | Tissue imaging using nonlinear laser scanning microscope |
| title_fullStr | Tissue imaging using nonlinear laser scanning microscope |
| title_full_unstemmed | Tissue imaging using nonlinear laser scanning microscope |
| title_short | Tissue imaging using nonlinear laser scanning microscope |
| title_sort | tissue imaging using nonlinear laser scanning microscope |
| topic | DRNTU::Science::Physics::Optics and light |
| url | http://hdl.handle.net/10356/75631 |
| work_keys_str_mv | AT taykennethzihan tissueimagingusingnonlinearlaserscanningmicroscope |