Optimizing the synthesis of teixobactin and investigating the effects of cationicity of the macrocyclic pharmocophore on antibacterial activity
Following the widespread use and abuse of antibiotics, bacteria have evolved a diverse array of strategies to evade elimination by these antimicrobial drugs, a phenomenon commonly known as antibiotic resistance. The capacity for bacteria to develop resistance against multiple types of antibiotics p...
Main Author: | Ng, Belle Min Yee |
---|---|
Other Authors: | Liu Chuan Fa |
Format: | Final Year Project (FYP) |
Language: | English |
Published: |
2019
|
Subjects: | |
Online Access: | http://hdl.handle.net/10356/77124 |
Similar Items
-
The necessity of d-Thr in the new antibiotic teixobactin : a molecular dynamics study
by: Liu, Yang, et al.
Published: (2020) -
Total synthesis of teixobactin
by: Kang Jin, et al.
Published: (2016-08-01) -
New route to macrocycles : synthesis of macrocycle via McMurry coupling
by: Fan, Huiyi
Published: (2009) -
Structure and internal organization of overcharged cationic-lipid/peptide/DNA self-assembly complexes
by: Yan, Jiang, et al.
Published: (2013) -
Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA)
by: Ruba Malkawi, et al.
Published: (2018-10-01)