Structure of the human telomere in Na+ solution : an antiparallel (2+2) G-quadruplex scaffold reveals additional diversity
Single-stranded DNA overhangs at the ends of human telomeric repeats are capable of adopting four-stranded G-quadruplex structures, which could serve as potential anticancer targets. Out of the five reported intramolecular human telomeric G-quadruplex structures, four were formed in the presence of...
Main Authors: | Lim, Kah Wai, Ng, Veronica Chinn Min, Martin-Pintado, Nerea, Heddi, Brahim, Phan, Anh Tuan |
---|---|
Other Authors: | School of Biological Sciences |
Format: | Journal Article |
Language: | English |
Published: |
2014
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/79374 http://hdl.handle.net/10220/18590 |
Similar Items
-
Functional and structural studies of the flavivirus RNA-dependent RNA polymerase
by: Yap, Thai Leong
Published: (2009) -
Molecular recognition in protein-DNA assemblies
by: Davey, Curt Alexander
Published: (2009) -
Synthesis and telomeric G-quadruplex-stabilizing ability of macrocyclic hexaoxazoles bearing three side chains
by: Ma, Yue, et al.
Published: (2019) -
G-quadruplex structure of an anti-proliferative DNA sequence
by: Do, Ngoc Quang, et al.
Published: (2017) -
The role of growth factor receptor bound protein 2 (GRB2) in gain of function of mutant p53.
by: Lau, Sok Ting.
Published: (2013)