Melanoma-initiating cells exploit M2 macrophage TGFβ and arginase pathway for survival and proliferation
M2 macrophages promote tumor growth and metastasis, but their interactions with specific tumor cell populations are poorly characterized. Using a mouse model of spontaneous melanoma, we showed that CD34- but not CD34+ tumor-initiating cells (TICs) depend on M2 macrophages for survival and proliferat...
| Main Authors: | , , , , , , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/79494 http://hdl.handle.net/10220/24702 http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path[]=2482 |