Photoacoustic phasoscopy super-contrast imaging correlating optical absorption and scattering

Phasoscopy is a recently proposed concept correlating electromagnetic (EM) absorption and scattering properties based on energy conservation. Phase information can be extracted from EM absorption induced acoustic wave and scattered EM wave for biological tissue characterization. In this paper, a nov...

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Main Authors: Gao, Fei, Feng, Xiaohua, Zheng, Yuanjin
Other Authors: Oraevsky, Alexander A.
Format: Conference Paper
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/79655
http://hdl.handle.net/10220/20445
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author Gao, Fei
Feng, Xiaohua
Zheng, Yuanjin
author2 Oraevsky, Alexander A.
author_facet Oraevsky, Alexander A.
Gao, Fei
Feng, Xiaohua
Zheng, Yuanjin
author_sort Gao, Fei
collection NTU
description Phasoscopy is a recently proposed concept correlating electromagnetic (EM) absorption and scattering properties based on energy conservation. Phase information can be extracted from EM absorption induced acoustic wave and scattered EM wave for biological tissue characterization. In this paper, a novel imaging modality, termed photoacoustic phasoscopy (PAPS) imaging, is proposed and verified experimentally based on phasoscopy concept with laser illumination. Both endogeneous photoacoustic wave and scattered photons are collected simultaneously to extract the phase information, and phasoscopy image is then reconstructed by mapping phase distribution. The phasoscopy imaging experiments on vessel-mimicking phantom and ex vivo porcine tissues demonstrate significantly improved contrast than conventional photoacoustic imaging.
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spelling ntu-10356/796552020-03-07T13:24:43Z Photoacoustic phasoscopy super-contrast imaging correlating optical absorption and scattering Gao, Fei Feng, Xiaohua Zheng, Yuanjin Oraevsky, Alexander A. Wang, Lihong V. School of Electrical and Electronic Engineering SPIE BiOS DRNTU::Engineering::Electrical and electronic engineering::Optics, optoelectronics, photonics Phasoscopy is a recently proposed concept correlating electromagnetic (EM) absorption and scattering properties based on energy conservation. Phase information can be extracted from EM absorption induced acoustic wave and scattered EM wave for biological tissue characterization. In this paper, a novel imaging modality, termed photoacoustic phasoscopy (PAPS) imaging, is proposed and verified experimentally based on phasoscopy concept with laser illumination. Both endogeneous photoacoustic wave and scattered photons are collected simultaneously to extract the phase information, and phasoscopy image is then reconstructed by mapping phase distribution. The phasoscopy imaging experiments on vessel-mimicking phantom and ex vivo porcine tissues demonstrate significantly improved contrast than conventional photoacoustic imaging. Published version 2014-09-01T04:31:03Z 2019-12-06T13:30:12Z 2014-09-01T04:31:03Z 2019-12-06T13:30:12Z 2014 2014 Conference Paper Gao, F., Feng, X., & Zheng, Y. (2014). Photoacoustic phasoscopy super-contrast imaging correlating optical absorption and scattering. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 8943. https://hdl.handle.net/10356/79655 http://hdl.handle.net/10220/20445 10.1117/12.2041867 en © 2014 SPIE. This paper was published in Progress in Biomedical Optics and Imaging - Proceedings of SPIE and is made available as an electronic reprint (preprint) with permission of SPIE. The paper can be found at the following official DOI: [http://dx.doi.org/10.1117/12.2041867]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. application/pdf
spellingShingle DRNTU::Engineering::Electrical and electronic engineering::Optics, optoelectronics, photonics
Gao, Fei
Feng, Xiaohua
Zheng, Yuanjin
Photoacoustic phasoscopy super-contrast imaging correlating optical absorption and scattering
title Photoacoustic phasoscopy super-contrast imaging correlating optical absorption and scattering
title_full Photoacoustic phasoscopy super-contrast imaging correlating optical absorption and scattering
title_fullStr Photoacoustic phasoscopy super-contrast imaging correlating optical absorption and scattering
title_full_unstemmed Photoacoustic phasoscopy super-contrast imaging correlating optical absorption and scattering
title_short Photoacoustic phasoscopy super-contrast imaging correlating optical absorption and scattering
title_sort photoacoustic phasoscopy super contrast imaging correlating optical absorption and scattering
topic DRNTU::Engineering::Electrical and electronic engineering::Optics, optoelectronics, photonics
url https://hdl.handle.net/10356/79655
http://hdl.handle.net/10220/20445
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