Access to pyridines via DMAP-catalyzed activation of α-chloro acetic ester to react with unsaturated imines
Facile access to trisubstituted pyridines from α-chloro acetic ester and unsaturated imines is achieved. DMAP-catalyzed activation of ester to form an enolate intermediate constitutes a key reaction step. On the application side, the wide availability and low cost of the substrates and catalysts mak...
Main Authors: | Chi, Robin Yonggui, Hao, Lin, Chen, Xingkuan, Chen, Shaojin, Jiang, Ke, Torres, Jaume |
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Other Authors: | School of Physical and Mathematical Sciences |
Format: | Journal Article |
Language: | English |
Published: |
2014
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/79664 http://hdl.handle.net/10220/23927 |
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