Single-Cell DNA-methylation analysis reveals epigenetic chimerism in preimplantation embryos

Epigenetic alterations are increasingly recognized as causes of human cancers and disease. These aberrations are likely to arise during genomic reprogramming in mammalian preimplantation embryos, when their epigenomes are most vulnerable. However, this process is only partially understood because of...

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Bibliographic Details
Main Authors: Lorthongpanich, Chanchao, Cheow, Lih Feng, Balu, Sathish, Quake, Stephen R., Knowles, Barbara B., Burkholder, William F., Solter, Davor, Messerschmidt, Daniel M.
Format: Journal Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/79976
http://hdl.handle.net/10220/19858