Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection
Introduction: Globally, extra-intestinal pathogenic Escherichia coli are one of the predominant causative agents of bacteraemia. Case presentation: This case report outlines a presentation of community-acquired pyelonephritis and secondary bloodstream infection in an 81-year-old man. Laboratory inv...
| Main Authors: | , , , , , |
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| Format: | Journal Article |
| Language: | English |
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2017
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| Online Access: | https://hdl.handle.net/10356/80781 http://hdl.handle.net/10220/42230 |
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| author | Mac Aogáin, Micheál Miajlovic, Helen Moloney, Geraldine Chotirmall, Sanjay Haresh Rogers, Thomas R. Smith, Stephen G. J. |
| author2 | Lee Kong Chian School of Medicine (LKCMedicine) |
| author_facet | Lee Kong Chian School of Medicine (LKCMedicine) Mac Aogáin, Micheál Miajlovic, Helen Moloney, Geraldine Chotirmall, Sanjay Haresh Rogers, Thomas R. Smith, Stephen G. J. |
| author_sort | Mac Aogáin, Micheál |
| collection | NTU |
| description | Introduction: Globally, extra-intestinal pathogenic Escherichia coli are one of the predominant causative agents of bacteraemia.
Case presentation: This case report outlines a presentation of community-acquired pyelonephritis and secondary bloodstream infection in an 81-year-old man. Laboratory investigations revealed that the causative isolate was a multi-drug-resistant E. coli of a novel multi-locus sequence type. This sequence type (ST) was designated ST-458 and was most closely related to the globally prevalent ST-131 lineage.
Conclusion: This is the first report of a novel E. coli ST, ST-458, which caused pyelonephritis and bacteraemia. |
| first_indexed | 2025-02-19T03:57:45Z |
| format | Journal Article |
| id | ntu-10356/80781 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2025-02-19T03:57:45Z |
| publishDate | 2017 |
| record_format | dspace |
| spelling | ntu-10356/807812020-11-01T05:32:20Z Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection Mac Aogáin, Micheál Miajlovic, Helen Moloney, Geraldine Chotirmall, Sanjay Haresh Rogers, Thomas R. Smith, Stephen G. J. Lee Kong Chian School of Medicine (LKCMedicine) Escherichia coli ST-458 Bacteraemia Introduction: Globally, extra-intestinal pathogenic Escherichia coli are one of the predominant causative agents of bacteraemia. Case presentation: This case report outlines a presentation of community-acquired pyelonephritis and secondary bloodstream infection in an 81-year-old man. Laboratory investigations revealed that the causative isolate was a multi-drug-resistant E. coli of a novel multi-locus sequence type. This sequence type (ST) was designated ST-458 and was most closely related to the globally prevalent ST-131 lineage. Conclusion: This is the first report of a novel E. coli ST, ST-458, which caused pyelonephritis and bacteraemia. Published version 2017-04-06T04:50:16Z 2019-12-06T13:58:47Z 2017-04-06T04:50:16Z 2019-12-06T13:58:47Z 2016 Journal Article Mac Aogáin, M., Miajlovic, H., Moloney, G., Chotirmall, S. H., Rogers, T. R., & Smith, S. G. J. (2016). Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection. JMM Case Reports, 3, 1-4. https://hdl.handle.net/10356/80781 http://hdl.handle.net/10220/42230 10.1099/jmmcr.0.005061 en JMM Case Reports © 2016 The Authors (published by Microbiology Society). This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/). 4 p. application/pdf |
| spellingShingle | Escherichia coli ST-458 Bacteraemia Mac Aogáin, Micheál Miajlovic, Helen Moloney, Geraldine Chotirmall, Sanjay Haresh Rogers, Thomas R. Smith, Stephen G. J. Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection |
| title | Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection |
| title_full | Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection |
| title_fullStr | Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection |
| title_full_unstemmed | Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection |
| title_short | Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection |
| title_sort | identification of a novel sequence type of escherichia coli as the causative agent of pyelonephritis and bloodstream infection |
| topic | Escherichia coli ST-458 Bacteraemia |
| url | https://hdl.handle.net/10356/80781 http://hdl.handle.net/10220/42230 |
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