Microarray profiling shows distinct differences between primary tumors and commonly used preclinical models in hepatocellular carcinoma

Microarray profiling shows distinct differences between primary tumors and commonly used preclinical models in hepatocellular carcinoma

Background: Despite advances in therapeutics, outcomes for hepatocellular carcinoma (HCC) remain poor and there is an urgent need for efficacious systemic therapy. Unfortunately, drugs that are successful in preclinical studies often fail in the clinical setting, and we hypothesize that this is due...

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Bibliographic Details
Main Authors: Wang, Weining, Iyer, N. Gopalakrishna, Tay, Hsien Ts’ung, Wu, Yonghui, Lim, Tony K. H., Zheng, Lin, Song, In Chin, Kwoh, Chee Keong, Huynh, Hung, Tan, Patrick O. B., Chow, Pierce K. H.
Other Authors: School of Computer Engineering
Format: Journal Article
Language:English
Published: 2015
Subjects:
Orthotopic
Xenograft
HepG2 cell line
Hepatocellular carcinoma
Ectopic
Online Access:https://hdl.handle.net/10356/80966
http://hdl.handle.net/10220/38996

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