Neurofilament light as a blood biomarker for neurodegeneration in down syndrome

Background Down syndrome (DS) may be considered a genetic form of Alzheimer’s disease (AD) due to universal development of AD neuropathology, but diagnosis and treatment trials are hampered by a lack of reliable blood biomarkers. A potential biomarker is neurofilament light (NF-L), due to its ass...

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Bibliographic Details
Main Authors: Strydom, Andre, Heslegrave, Amanda, Startin, Carla M., Mok, Kin Y., Hardy, John, Groet, Jurgen, Nizetic, Dean, Zetterberg, Henrik
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/81011
http://hdl.handle.net/10220/45065