Removal of concentrated sulfamethazine by acclimatized aerobic sludge and possible metabolic products
This article examined the biological removal of high concentrated sulfamethazine (SMZ) antibiotics by the acclimatized activated sludge in lab-scale SBRs system. The removal of SMZ was characterized by a quick adsorption and a slow process of biodegradation. The adsorption capacity of activated slud...
| Main Authors: | , , , |
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| Format: | Journal Article |
| Language: | English |
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2015
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| Online Access: | https://hdl.handle.net/10356/81074 http://hdl.handle.net/10220/39119 |
| _version_ | 1811689548136054784 |
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| author | Yang, Na Wan, Junfeng Zhao, Shiju Wang, Yan |
| author2 | School of Civil and Environmental Engineering |
| author_facet | School of Civil and Environmental Engineering Yang, Na Wan, Junfeng Zhao, Shiju Wang, Yan |
| author_sort | Yang, Na |
| collection | NTU |
| description | This article examined the biological removal of high concentrated sulfamethazine (SMZ) antibiotics by the acclimatized activated sludge in lab-scale SBRs system. The removal of SMZ was characterized by a quick adsorption and a slow process of biodegradation. The adsorption capacity of activated sludge for SMZ was 44 and 47 µg SMZ/g SS, respectively, with the initial SMZ concentrations of 1 and 2 mg/L. The adsorption process fitted pseudo-second-order kinetic model. In a series of batch studies, with the increase of initial SMZ concentration that were 1, 2, 3, 5, 7 and 9 mg/L, 56.0%, 51.3%, 42.2%, 29.5%, 25.0% and 20.8% of influent SMZ were biodegraded within 24 h of biological reaction, respectively. The Monod equation applied to simulate SMZ biodegradation had a good coefficient of determination (R2 > 0.99). Furthermore, the results of HPLC demonstrated that the SMZ was not completely removed by the acclimatized activated sludge. From the analysis of LC-MS, 4 intermediates of SMZ biodegradation were identified: Sulfanilic Acid, 4-amino-N-(4,6-dimethyl-2 pyrimidin) benzene sulfonamide, N-(4,6-dimethyl-2-pyrimidin)-4-N-(benzene sulfonamide) benzene sulfonamide, N-(4,6-dimethyl-2-pyrimidin)-4-N-(4,6-dimethyl pyrimidine) benzene sulfonamide, and N-(4,6-dimethyl-2-pyrimidin)-4-N-(3-dimethyl-4-N sodium benzene sulfonamide) benzene sulfonamide. |
| first_indexed | 2024-10-01T05:49:51Z |
| format | Journal Article |
| id | ntu-10356/81074 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:49:51Z |
| publishDate | 2015 |
| record_format | dspace |
| spelling | ntu-10356/810742022-02-16T16:27:01Z Removal of concentrated sulfamethazine by acclimatized aerobic sludge and possible metabolic products Yang, Na Wan, Junfeng Zhao, Shiju Wang, Yan School of Civil and Environmental Engineering Nanyang Environment and Water Research Institute Adsorption Metabolites Sulfamethazine (SMZ) Acclimatized activated sludge Biodegradation This article examined the biological removal of high concentrated sulfamethazine (SMZ) antibiotics by the acclimatized activated sludge in lab-scale SBRs system. The removal of SMZ was characterized by a quick adsorption and a slow process of biodegradation. The adsorption capacity of activated sludge for SMZ was 44 and 47 µg SMZ/g SS, respectively, with the initial SMZ concentrations of 1 and 2 mg/L. The adsorption process fitted pseudo-second-order kinetic model. In a series of batch studies, with the increase of initial SMZ concentration that were 1, 2, 3, 5, 7 and 9 mg/L, 56.0%, 51.3%, 42.2%, 29.5%, 25.0% and 20.8% of influent SMZ were biodegraded within 24 h of biological reaction, respectively. The Monod equation applied to simulate SMZ biodegradation had a good coefficient of determination (R2 > 0.99). Furthermore, the results of HPLC demonstrated that the SMZ was not completely removed by the acclimatized activated sludge. From the analysis of LC-MS, 4 intermediates of SMZ biodegradation were identified: Sulfanilic Acid, 4-amino-N-(4,6-dimethyl-2 pyrimidin) benzene sulfonamide, N-(4,6-dimethyl-2-pyrimidin)-4-N-(benzene sulfonamide) benzene sulfonamide, N-(4,6-dimethyl-2-pyrimidin)-4-N-(4,6-dimethyl pyrimidine) benzene sulfonamide, and N-(4,6-dimethyl-2-pyrimidin)-4-N-(3-dimethyl-4-N sodium benzene sulfonamide) benzene sulfonamide. Published version 2015-12-17T03:04:25Z 2019-12-06T14:20:53Z 2015-12-17T03:04:25Z 2019-12-06T14:20:53Z 2015 Journal Article Yang, N., Wan, J., Zhao, S., & Wang, Y. (2015). Removal of concentrated sulfamethazine by acclimatized aerobic sludge and possible metabolic products. PeerJ, 3, e1359-. https://hdl.handle.net/10356/81074 http://hdl.handle.net/10220/39119 10.7717/peerj.1359 26557437 en PeerJ © 2015 Yang et al. Distributed under Creative Commons CC-BY 4.0 15 p. application/pdf |
| spellingShingle | Adsorption Metabolites Sulfamethazine (SMZ) Acclimatized activated sludge Biodegradation Yang, Na Wan, Junfeng Zhao, Shiju Wang, Yan Removal of concentrated sulfamethazine by acclimatized aerobic sludge and possible metabolic products |
| title | Removal of concentrated sulfamethazine by acclimatized aerobic sludge and possible metabolic products |
| title_full | Removal of concentrated sulfamethazine by acclimatized aerobic sludge and possible metabolic products |
| title_fullStr | Removal of concentrated sulfamethazine by acclimatized aerobic sludge and possible metabolic products |
| title_full_unstemmed | Removal of concentrated sulfamethazine by acclimatized aerobic sludge and possible metabolic products |
| title_short | Removal of concentrated sulfamethazine by acclimatized aerobic sludge and possible metabolic products |
| title_sort | removal of concentrated sulfamethazine by acclimatized aerobic sludge and possible metabolic products |
| topic | Adsorption Metabolites Sulfamethazine (SMZ) Acclimatized activated sludge Biodegradation |
| url | https://hdl.handle.net/10356/81074 http://hdl.handle.net/10220/39119 |
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