Can the Wet – State Conductivity of Hydrogels be Improved by Incorporation of Spherical Conducting Nanoparticles?
In nerve and muscle regeneration applications, the incorporation of conducting elements into biocompatible materials has gained interest over the last few years, as it has been shown that electrical stimulation of some regenerating cells has a positive effect on their development. A variety of diffe...
| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2016
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| Online Access: | https://hdl.handle.net/10356/81873 http://hdl.handle.net/10220/39738 |
| _version_ | 1811691409458069504 |
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| author | Schirmer, Katharina Wright, Cody Warren, Holly Thompson, Brianna Quigley, Anita Kapsa, Robert Wallace, Gordon |
| author2 | School of Mechanical and Aerospace Engineering |
| author_facet | School of Mechanical and Aerospace Engineering Schirmer, Katharina Wright, Cody Warren, Holly Thompson, Brianna Quigley, Anita Kapsa, Robert Wallace, Gordon |
| author_sort | Schirmer, Katharina |
| collection | NTU |
| description | In nerve and muscle regeneration applications, the incorporation of conducting elements into biocompatible materials has gained interest over the last few years, as it has been shown that electrical stimulation of some regenerating cells has a positive effect on their development. A variety of different materials, ranging from graphene to conducting polymers, have been incorporated into hydrogels and increased conductivities have been reported. However, the majority of conductivity measurements are performed in a dry state, even though material blends are designed for applications in a wet state, in vivo environment. The focus of this work is to use polypyrrole nanoparticles to increase the wet–state conductivity of alginate to produce a conducting, easily processable, cell–supporting composite material. Characterization and purification of the conducting polymer nanoparticle dispersions, as well as electrochemical measurements, have been performed to assess conductivity of the nanoparticles and hydrogel composites in the wet state, in order to determine whether filling an ionically conducting hydrogel with electrically conductive nanoparticles will enhance the conductivity. It was determined that the introduction of spherical nanoparticles into alginate gel does not increase, but rather slightly reduces conductivity of the hydrogel in the wet state. |
| first_indexed | 2024-10-01T06:19:26Z |
| format | Journal Article |
| id | ntu-10356/81873 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T06:19:26Z |
| publishDate | 2016 |
| record_format | dspace |
| spelling | ntu-10356/818732023-03-04T17:13:44Z Can the Wet – State Conductivity of Hydrogels be Improved by Incorporation of Spherical Conducting Nanoparticles? Schirmer, Katharina Wright, Cody Warren, Holly Thompson, Brianna Quigley, Anita Kapsa, Robert Wallace, Gordon School of Mechanical and Aerospace Engineering Spherical Wet Conducting Hydrogels Be Nanoparticles Improved Incorporation Conductivity Can In nerve and muscle regeneration applications, the incorporation of conducting elements into biocompatible materials has gained interest over the last few years, as it has been shown that electrical stimulation of some regenerating cells has a positive effect on their development. A variety of different materials, ranging from graphene to conducting polymers, have been incorporated into hydrogels and increased conductivities have been reported. However, the majority of conductivity measurements are performed in a dry state, even though material blends are designed for applications in a wet state, in vivo environment. The focus of this work is to use polypyrrole nanoparticles to increase the wet–state conductivity of alginate to produce a conducting, easily processable, cell–supporting composite material. Characterization and purification of the conducting polymer nanoparticle dispersions, as well as electrochemical measurements, have been performed to assess conductivity of the nanoparticles and hydrogel composites in the wet state, in order to determine whether filling an ionically conducting hydrogel with electrically conductive nanoparticles will enhance the conductivity. It was determined that the introduction of spherical nanoparticles into alginate gel does not increase, but rather slightly reduces conductivity of the hydrogel in the wet state. Accepted version 2016-01-21T04:07:56Z 2019-12-06T14:42:03Z 2016-01-21T04:07:56Z 2019-12-06T14:42:03Z 2014 Journal Article Schirmer, K., Wright, C., Warren, H., Thompson, B., Quigley, A., Kapsa, R., et al. (2014). Can the Wet – State Conductivity of Hydrogels be Improved by Incorporation of Spherical Conducting Nanoparticles?. MRS Proceedings, 1717, 1-6. 0272-9172 https://hdl.handle.net/10356/81873 http://hdl.handle.net/10220/39738 10.1557/opl.2014.952 en Materials Research Society Symposium Proceedings © 2014 Materials Research Society. This is the author created version of a work that has been peer reviewed and accepted for publication by Materials Research Society Symposium Proceedings, Materials Research Society. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1557/opl.2014.952]. 6 p. application/pdf |
| spellingShingle | Spherical Wet Conducting Hydrogels Be Nanoparticles Improved Incorporation Conductivity Can Schirmer, Katharina Wright, Cody Warren, Holly Thompson, Brianna Quigley, Anita Kapsa, Robert Wallace, Gordon Can the Wet – State Conductivity of Hydrogels be Improved by Incorporation of Spherical Conducting Nanoparticles? |
| title | Can the Wet – State Conductivity of Hydrogels be Improved by Incorporation of Spherical Conducting Nanoparticles? |
| title_full | Can the Wet – State Conductivity of Hydrogels be Improved by Incorporation of Spherical Conducting Nanoparticles? |
| title_fullStr | Can the Wet – State Conductivity of Hydrogels be Improved by Incorporation of Spherical Conducting Nanoparticles? |
| title_full_unstemmed | Can the Wet – State Conductivity of Hydrogels be Improved by Incorporation of Spherical Conducting Nanoparticles? |
| title_short | Can the Wet – State Conductivity of Hydrogels be Improved by Incorporation of Spherical Conducting Nanoparticles? |
| title_sort | can the wet state conductivity of hydrogels be improved by incorporation of spherical conducting nanoparticles |
| topic | Spherical Wet Conducting Hydrogels Be Nanoparticles Improved Incorporation Conductivity Can |
| url | https://hdl.handle.net/10356/81873 http://hdl.handle.net/10220/39738 |
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