Tropomyosin movement is described by a quantitative high-resolution model of X-ray diffraction of contracting muscle
Contraction of skeletal and cardiac muscle is controlled by Ca2+ ions via regulatory proteins, troponin (Tn) and tropomyosin (Tpm) associated with the thin actin filaments in sarcomeres. In the absence of Ca2+, Tn-C binds actin and shifts the Tpm strand to a position where it blocks myosin binding t...
Main Authors: | Koubassova, Natalia A., Bershitsky, Sergey Y., Ferenczi, Michael Alan, Narayanan, Theyencheri, Tsaturyan, Andrey K. |
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Other Authors: | Lee Kong Chian School of Medicine (LKCMedicine) |
Format: | Journal Article |
Language: | English |
Published: |
2017
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/82598 http://hdl.handle.net/10220/42316 |
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