Nitrogen and phosphorus co-doped graphene quantum dots: synthesis from adenosine triphosphate, optical properties, and cellular imaging
Graphene quantum dots (GQDs) are emerging zero-dimensional materials promising a wide spectrum of applications, particularly, as superior fluorescent reporters for bio-imaging and optical sensing. Heteroatom doping can endow GQDs with new or improved photoluminescence properties. Here, we demonstrat...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal Article |
| Language: | English |
| Published: |
2016
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| Online Access: | https://hdl.handle.net/10356/82654 http://hdl.handle.net/10220/40299 |
| _version_ | 1811680186973814784 |
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| author | Ananthanarayanan, Arundithi Wang, Yue Routh, Parimal Sk, Mahasin Alam Than, Aung Lin, Ming Zhang, Jie Chen, Jie Sun, Handong Chen, Peng |
| author2 | School of Chemical and Biomedical Engineering |
| author_facet | School of Chemical and Biomedical Engineering Ananthanarayanan, Arundithi Wang, Yue Routh, Parimal Sk, Mahasin Alam Than, Aung Lin, Ming Zhang, Jie Chen, Jie Sun, Handong Chen, Peng |
| author_sort | Ananthanarayanan, Arundithi |
| collection | NTU |
| description | Graphene quantum dots (GQDs) are emerging zero-dimensional materials promising a wide spectrum of applications, particularly, as superior fluorescent reporters for bio-imaging and optical sensing. Heteroatom doping can endow GQDs with new or improved photoluminescence properties. Here, we demonstrate a simple strategy for the synthesis of nitrogen and phosphorus co-doped GQDs from a single biomolecule precursor (adenosine triphosphate – ATP). Such ATP-GQDs exhibit high fluorescence quantum yield, strong two-photon upconversion, small molecular weight, high photostability, and good biocompatibility. Furthermore, transferrin conjugated ATP-GQDs have been used for imaging and real-time tracking of transferrin receptors in live cells. |
| first_indexed | 2024-10-01T03:21:03Z |
| format | Journal Article |
| id | ntu-10356/82654 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T03:21:03Z |
| publishDate | 2016 |
| record_format | dspace |
| spelling | ntu-10356/826542023-02-28T19:50:36Z Nitrogen and phosphorus co-doped graphene quantum dots: synthesis from adenosine triphosphate, optical properties, and cellular imaging Ananthanarayanan, Arundithi Wang, Yue Routh, Parimal Sk, Mahasin Alam Than, Aung Lin, Ming Zhang, Jie Chen, Jie Sun, Handong Chen, Peng School of Chemical and Biomedical Engineering School of Physical and Mathematical Sciences Adenosinetriphosphate cytology Graphene quantum dots (GQDs) are emerging zero-dimensional materials promising a wide spectrum of applications, particularly, as superior fluorescent reporters for bio-imaging and optical sensing. Heteroatom doping can endow GQDs with new or improved photoluminescence properties. Here, we demonstrate a simple strategy for the synthesis of nitrogen and phosphorus co-doped GQDs from a single biomolecule precursor (adenosine triphosphate – ATP). Such ATP-GQDs exhibit high fluorescence quantum yield, strong two-photon upconversion, small molecular weight, high photostability, and good biocompatibility. Furthermore, transferrin conjugated ATP-GQDs have been used for imaging and real-time tracking of transferrin receptors in live cells. NRF (Natl Research Foundation, S’pore) ASTAR (Agency for Sci., Tech. and Research, S’pore) MOE (Min. of Education, S’pore) NMRC (Natl Medical Research Council, S’pore) MOH (Min. of Health, S’pore) Published version 2016-03-18T05:44:23Z 2019-12-06T14:59:46Z 2016-03-18T05:44:23Z 2019-12-06T14:59:46Z 2015 Journal Article Ananthanarayanan, A., Wang, Y., Routh, P., Sk, M. A., Than, A., Lin, M., et al. (2015). Nitrogen and phosphorus co-doped graphene quantum dots: synthesis from adenosine triphosphate, optical properties, and cellular imaging. Nanoscale, 7(17), 8159-8165. 2040-3364 https://hdl.handle.net/10356/82654 http://hdl.handle.net/10220/40299 10.1039/C5NR01519G en Nanoscale This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. 7 p. application/pdf |
| spellingShingle | Adenosinetriphosphate cytology Ananthanarayanan, Arundithi Wang, Yue Routh, Parimal Sk, Mahasin Alam Than, Aung Lin, Ming Zhang, Jie Chen, Jie Sun, Handong Chen, Peng Nitrogen and phosphorus co-doped graphene quantum dots: synthesis from adenosine triphosphate, optical properties, and cellular imaging |
| title | Nitrogen and phosphorus co-doped graphene quantum dots: synthesis from adenosine triphosphate, optical properties, and cellular imaging |
| title_full | Nitrogen and phosphorus co-doped graphene quantum dots: synthesis from adenosine triphosphate, optical properties, and cellular imaging |
| title_fullStr | Nitrogen and phosphorus co-doped graphene quantum dots: synthesis from adenosine triphosphate, optical properties, and cellular imaging |
| title_full_unstemmed | Nitrogen and phosphorus co-doped graphene quantum dots: synthesis from adenosine triphosphate, optical properties, and cellular imaging |
| title_short | Nitrogen and phosphorus co-doped graphene quantum dots: synthesis from adenosine triphosphate, optical properties, and cellular imaging |
| title_sort | nitrogen and phosphorus co doped graphene quantum dots synthesis from adenosine triphosphate optical properties and cellular imaging |
| topic | Adenosinetriphosphate cytology |
| url | https://hdl.handle.net/10356/82654 http://hdl.handle.net/10220/40299 |
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