Enhancement and bias removal of optical coherence tomography images: An iterative approach with adaptive bilateral filtering

Optical coherence tomography (OCT) has continually evolved and expanded as one of the most valuable routine tests in ophthalmology. However, noise (speckle) in the acquired images causes quality degradation of OCT images and makes it difficult to analyze the acquired images. In this paper, an iterat...

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Main Authors: Palanisamy, P., Rajan, Jeny, Xiaojun, Yu, Sudeep, P. V., Issac Niwas, Swamidoss, Wang, Xianghong, Luo, Yuemei, Liu, Linbo
Other Authors: School of Chemical and Biomedical Engineering
Format: Journal Article
Language:English
Published: 2017
Subjects:
Online Access:https://hdl.handle.net/10356/83116
http://hdl.handle.net/10220/42441
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author Palanisamy, P.
Rajan, Jeny
Xiaojun, Yu
Sudeep, P. V.
Issac Niwas, Swamidoss
Wang, Xianghong
Luo, Yuemei
Liu, Linbo
author2 School of Chemical and Biomedical Engineering
author_facet School of Chemical and Biomedical Engineering
Palanisamy, P.
Rajan, Jeny
Xiaojun, Yu
Sudeep, P. V.
Issac Niwas, Swamidoss
Wang, Xianghong
Luo, Yuemei
Liu, Linbo
author_sort Palanisamy, P.
collection NTU
description Optical coherence tomography (OCT) has continually evolved and expanded as one of the most valuable routine tests in ophthalmology. However, noise (speckle) in the acquired images causes quality degradation of OCT images and makes it difficult to analyze the acquired images. In this paper, an iterative approach based on bilateral filtering is proposed for speckle reduction in multiframe OCT data. Gamma noise model is assumed for the observed OCT image. First, the adaptive version of the conventional bilateral filter is applied to enhance the multiframe OCT data and then the bias due to noise is reduced from each of the filtered frames. These unbiased filtered frames are then refined using an iterative approach. Finally, these refined frames are averaged to produce the denoised OCT image. Experimental results on phantom images and real OCT retinal images demonstrate the effectiveness of the proposed filter.
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spelling ntu-10356/831162020-03-07T11:35:26Z Enhancement and bias removal of optical coherence tomography images: An iterative approach with adaptive bilateral filtering Palanisamy, P. Rajan, Jeny Xiaojun, Yu Sudeep, P. V. Issac Niwas, Swamidoss Wang, Xianghong Luo, Yuemei Liu, Linbo School of Chemical and Biomedical Engineering School of Electrical and Electronic Engineering Bilateral filtering Denoising Optical coherence tomography (OCT) has continually evolved and expanded as one of the most valuable routine tests in ophthalmology. However, noise (speckle) in the acquired images causes quality degradation of OCT images and makes it difficult to analyze the acquired images. In this paper, an iterative approach based on bilateral filtering is proposed for speckle reduction in multiframe OCT data. Gamma noise model is assumed for the observed OCT image. First, the adaptive version of the conventional bilateral filter is applied to enhance the multiframe OCT data and then the bias due to noise is reduced from each of the filtered frames. These unbiased filtered frames are then refined using an iterative approach. Finally, these refined frames are averaged to produce the denoised OCT image. Experimental results on phantom images and real OCT retinal images demonstrate the effectiveness of the proposed filter. NMRC (Natl Medical Research Council, S’pore) MOE (Min. of Education, S’pore) Accepted version 2017-05-17T03:57:26Z 2019-12-06T15:12:08Z 2017-05-17T03:57:26Z 2019-12-06T15:12:08Z 2016 Journal Article Sudeep, P. V., Issac Niwas, S., Palanisamy, P., Rajan, J., Xiaojun, Y., Wang, X., et al. (2016). Enhancement and bias removal of optical coherence tomography images: An iterative approach with adaptive bilateral filtering. Computers in Biology and Medicine, 71, 97-107. 0010-4825 https://hdl.handle.net/10356/83116 http://hdl.handle.net/10220/42441 10.1016/j.compbiomed.2016.02.003 en Computers in Biology and Medicine © 2016 Elsevier Ltd. This is the author created version of a work that has been peer reviewed and accepted for publication by Computers in Biology and Medicine, Elsevier. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1016/j.compbiomed.2016.02.003]. 38 p. application/pdf
spellingShingle Bilateral filtering
Denoising
Palanisamy, P.
Rajan, Jeny
Xiaojun, Yu
Sudeep, P. V.
Issac Niwas, Swamidoss
Wang, Xianghong
Luo, Yuemei
Liu, Linbo
Enhancement and bias removal of optical coherence tomography images: An iterative approach with adaptive bilateral filtering
title Enhancement and bias removal of optical coherence tomography images: An iterative approach with adaptive bilateral filtering
title_full Enhancement and bias removal of optical coherence tomography images: An iterative approach with adaptive bilateral filtering
title_fullStr Enhancement and bias removal of optical coherence tomography images: An iterative approach with adaptive bilateral filtering
title_full_unstemmed Enhancement and bias removal of optical coherence tomography images: An iterative approach with adaptive bilateral filtering
title_short Enhancement and bias removal of optical coherence tomography images: An iterative approach with adaptive bilateral filtering
title_sort enhancement and bias removal of optical coherence tomography images an iterative approach with adaptive bilateral filtering
topic Bilateral filtering
Denoising
url https://hdl.handle.net/10356/83116
http://hdl.handle.net/10220/42441
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