Single-camera full-range high-resolution spectral domain optical coherence tomography
We developed spectral domain optical coherence tomography using a dual-channel spectrometer for complex conjugate artifacts (CCA) suppression. We used a three-line charge coupled device to simultaneously detect two interferometric spectra with 2𝜋/32π/3 phase difference. The complex interferometric s...
| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
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2017
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| Online Access: | https://hdl.handle.net/10356/83118 http://hdl.handle.net/10220/42397 |
| _version_ | 1826115312084320256 |
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| author | Bo, En Chen, Si Cui, Dongyao Chen, Shi Yu, Xiaojun Luo, Yuemei Liu, Linbo |
| author2 | School of Chemical and Biomedical Engineering |
| author_facet | School of Chemical and Biomedical Engineering Bo, En Chen, Si Cui, Dongyao Chen, Shi Yu, Xiaojun Luo, Yuemei Liu, Linbo |
| author_sort | Bo, En |
| collection | NTU |
| description | We developed spectral domain optical coherence tomography using a dual-channel spectrometer for complex conjugate artifacts (CCA) suppression. We used a three-line charge coupled device to simultaneously detect two interferometric spectra with 2𝜋/32π/3 phase difference. The complex interferometric signal was reconstructed by trigonometric manipulation of two real interferometric spectra, and then full-range images were obtained by use of inverse Fourier transform. Artifacts at direct current (DC) and the ghost remnant of the CCA are common issues with the previously reported two-spectrometer method because the slight mismatching between two spectral detection channels had strong negative effects on CCA suppression and appeared to be the limiting factor on system performance. This novel dual-channel spectrometer uses the same spectrometer optics for the two spectral detection channels and, therefore, achieves better matching between two spectral detection channels and consequently better performance in CCA suppression as compared with the dual spectrometer solution. Full-range imaging with CCA suppression up to ∼25 dB∼25 dB was demonstrated when imaging an attenuated reflector. The efficacy of both CCA and DC suppressions also was validated by imaging the anterior segment of a rat eye ex vivo. The quality of CCA-suppressed images was significantly improved with regard to those obtained with the dual-spectrometer design. |
| first_indexed | 2024-10-01T03:53:27Z |
| format | Journal Article |
| id | ntu-10356/83118 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T03:53:27Z |
| publishDate | 2017 |
| record_format | dspace |
| spelling | ntu-10356/831182020-03-07T11:35:26Z Single-camera full-range high-resolution spectral domain optical coherence tomography Bo, En Chen, Si Cui, Dongyao Chen, Shi Yu, Xiaojun Luo, Yuemei Liu, Linbo School of Chemical and Biomedical Engineering School of Electrical and Electronic Engineering High-resolution spectral Optical coherence tomography We developed spectral domain optical coherence tomography using a dual-channel spectrometer for complex conjugate artifacts (CCA) suppression. We used a three-line charge coupled device to simultaneously detect two interferometric spectra with 2𝜋/32π/3 phase difference. The complex interferometric signal was reconstructed by trigonometric manipulation of two real interferometric spectra, and then full-range images were obtained by use of inverse Fourier transform. Artifacts at direct current (DC) and the ghost remnant of the CCA are common issues with the previously reported two-spectrometer method because the slight mismatching between two spectral detection channels had strong negative effects on CCA suppression and appeared to be the limiting factor on system performance. This novel dual-channel spectrometer uses the same spectrometer optics for the two spectral detection channels and, therefore, achieves better matching between two spectral detection channels and consequently better performance in CCA suppression as compared with the dual spectrometer solution. Full-range imaging with CCA suppression up to ∼25 dB∼25 dB was demonstrated when imaging an attenuated reflector. The efficacy of both CCA and DC suppressions also was validated by imaging the anterior segment of a rat eye ex vivo. The quality of CCA-suppressed images was significantly improved with regard to those obtained with the dual-spectrometer design. NMRC (Natl Medical Research Council, S’pore) MOE (Min. of Education, S’pore) 2017-05-12T07:49:48Z 2019-12-06T15:12:10Z 2017-05-12T07:49:48Z 2019-12-06T15:12:10Z 2017 Journal Article Bo, E., Chen, S., Cui, D., Chen, S., Yu, X., Luo, Y., et al. (2017). Single-camera full-range high-resolution spectral domain optical coherence tomography. Applied Optics, 56(3), 470-475. 1559-128X https://hdl.handle.net/10356/83118 http://hdl.handle.net/10220/42397 10.1364/AO.56.000470 en Applied Optics © 2017 Optical Society of America. 6 p. |
| spellingShingle | High-resolution spectral Optical coherence tomography Bo, En Chen, Si Cui, Dongyao Chen, Shi Yu, Xiaojun Luo, Yuemei Liu, Linbo Single-camera full-range high-resolution spectral domain optical coherence tomography |
| title | Single-camera full-range high-resolution spectral domain optical coherence tomography |
| title_full | Single-camera full-range high-resolution spectral domain optical coherence tomography |
| title_fullStr | Single-camera full-range high-resolution spectral domain optical coherence tomography |
| title_full_unstemmed | Single-camera full-range high-resolution spectral domain optical coherence tomography |
| title_short | Single-camera full-range high-resolution spectral domain optical coherence tomography |
| title_sort | single camera full range high resolution spectral domain optical coherence tomography |
| topic | High-resolution spectral Optical coherence tomography |
| url | https://hdl.handle.net/10356/83118 http://hdl.handle.net/10220/42397 |
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