An RRM–ZnF RNA recognition module targets RBM10 to exonic sequences to promote exon exclusion
RBM10 is an RNA-binding protein that plays an essential role in development and is frequently mutated in the context of human disease. RBM10 recognizes a diverse set of RNA motifs in introns and exons and regulates alternative splicing. However, the molecular mechanisms underlying this seemingly rel...
Main Authors: | Collins, Katherine M., Kainov, Yaroslav A., Christodolou, Evangelos, Ray, Debashish, Morris, Quaid, Hughes, Timothy, Taylor, Ian A., Makeyev, Eugene V., Ramos, Andres |
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Other Authors: | School of Biological Sciences |
Format: | Journal Article |
Language: | English |
Published: |
2017
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/83187 http://hdl.handle.net/10220/42476 |
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