Programmable Nano–Bio Interfaces for Functional Biointegrated Devices

A large amount of evidence has demonstrated the revolutionary role of nanosystems in the screening and shielding of biological systems. The explosive development of interfacing bioentities with programmable nanomaterials has conveyed the intriguing concept of nano–bio interfaces. Here, recent advanc...

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Main Authors: Cai, Pingqiang, Leow, Wan Ru, Wang, Xiaoyuan, Wu, Yun-Long, Chen, Xiaodong
Other Authors: School of Materials Science & Engineering
Format: Journal Article
Language:English
Published: 2017
Subjects:
Online Access:https://hdl.handle.net/10356/83303
http://hdl.handle.net/10220/42554
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author Cai, Pingqiang
Leow, Wan Ru
Wang, Xiaoyuan
Wu, Yun-Long
Chen, Xiaodong
author2 School of Materials Science & Engineering
author_facet School of Materials Science & Engineering
Cai, Pingqiang
Leow, Wan Ru
Wang, Xiaoyuan
Wu, Yun-Long
Chen, Xiaodong
author_sort Cai, Pingqiang
collection NTU
description A large amount of evidence has demonstrated the revolutionary role of nanosystems in the screening and shielding of biological systems. The explosive development of interfacing bioentities with programmable nanomaterials has conveyed the intriguing concept of nano–bio interfaces. Here, recent advances in functional biointegrated devices through the precise programming of nano–bio interactions are outlined, especially with regard to the rational assembly of constituent nanomaterials on multiple dimension scales (e.g., nanoparticles, nanowires, layered nanomaterials, and 3D-architectured nanomaterials), in order to leverage their respective intrinsic merits for different functions. Emerging nanotechnological strategies at nano–bio interfaces are also highlighted, such as multimodal diagnosis or “theragnostics”, synergistic and sequential therapeutics delivery, and stretchable and flexible nanoelectronic devices, and their implementation into a broad range of biointegrated devices (e.g., implantable, minimally invasive, and wearable devices). When utilized as functional modules of biointegrated devices, these programmable nano–bio interfaces will open up a new chapter for precision nanomedicine.
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spelling ntu-10356/833032020-06-01T10:21:20Z Programmable Nano–Bio Interfaces for Functional Biointegrated Devices Cai, Pingqiang Leow, Wan Ru Wang, Xiaoyuan Wu, Yun-Long Chen, Xiaodong School of Materials Science & Engineering biointegrated devices nanomedicine A large amount of evidence has demonstrated the revolutionary role of nanosystems in the screening and shielding of biological systems. The explosive development of interfacing bioentities with programmable nanomaterials has conveyed the intriguing concept of nano–bio interfaces. Here, recent advances in functional biointegrated devices through the precise programming of nano–bio interactions are outlined, especially with regard to the rational assembly of constituent nanomaterials on multiple dimension scales (e.g., nanoparticles, nanowires, layered nanomaterials, and 3D-architectured nanomaterials), in order to leverage their respective intrinsic merits for different functions. Emerging nanotechnological strategies at nano–bio interfaces are also highlighted, such as multimodal diagnosis or “theragnostics”, synergistic and sequential therapeutics delivery, and stretchable and flexible nanoelectronic devices, and their implementation into a broad range of biointegrated devices (e.g., implantable, minimally invasive, and wearable devices). When utilized as functional modules of biointegrated devices, these programmable nano–bio interfaces will open up a new chapter for precision nanomedicine. 2017-06-01T08:44:38Z 2019-12-06T15:19:36Z 2017-06-01T08:44:38Z 2019-12-06T15:19:36Z 2017 2017 Journal Article Cai, P., Leow, W. R., Wang, X., Wu, Y.-L., & Chen, X. (2017). Programmable Nano–Bio Interfaces for Functional Biointegrated Devices. Advanced Materials, 29(26), 1605529-. 0935-9648 https://hdl.handle.net/10356/83303 http://hdl.handle.net/10220/42554 10.1002/adma.201605529 201196 en Advanced Materials © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
spellingShingle biointegrated devices
nanomedicine
Cai, Pingqiang
Leow, Wan Ru
Wang, Xiaoyuan
Wu, Yun-Long
Chen, Xiaodong
Programmable Nano–Bio Interfaces for Functional Biointegrated Devices
title Programmable Nano–Bio Interfaces for Functional Biointegrated Devices
title_full Programmable Nano–Bio Interfaces for Functional Biointegrated Devices
title_fullStr Programmable Nano–Bio Interfaces for Functional Biointegrated Devices
title_full_unstemmed Programmable Nano–Bio Interfaces for Functional Biointegrated Devices
title_short Programmable Nano–Bio Interfaces for Functional Biointegrated Devices
title_sort programmable nano bio interfaces for functional biointegrated devices
topic biointegrated devices
nanomedicine
url https://hdl.handle.net/10356/83303
http://hdl.handle.net/10220/42554
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AT leowwanru programmablenanobiointerfacesforfunctionalbiointegrateddevices
AT wangxiaoyuan programmablenanobiointerfacesforfunctionalbiointegrateddevices
AT wuyunlong programmablenanobiointerfacesforfunctionalbiointegrateddevices
AT chenxiaodong programmablenanobiointerfacesforfunctionalbiointegrateddevices