Manipulating Magnetic 3D Spheroids in Hanging Drops for Applications in Tissue Engineering and Drug Screening
Magnetic spheroid manipulation can be carried out in hanging drops to generate distinctly structured heterotypic microtissues through sequential addition of cells or spheroid to homotypic spheroids. These spheroids can also be incorporated in a droplet-based assay to screen for therapeutic efficacy...
| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/83848 http://hdl.handle.net/10220/41500 |
| _version_ | 1811693327882387456 |
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| author | Ho, Vincent H. B. Guo, Wei Mei Huang, Charlotte L. Ho, Shu Fen Chaw, Su Yin Tan, Ern Yu Ng, Kee Woei Loo, Joachim Say Chye |
| author2 | School of Materials Science & Engineering |
| author_facet | School of Materials Science & Engineering Ho, Vincent H. B. Guo, Wei Mei Huang, Charlotte L. Ho, Shu Fen Chaw, Su Yin Tan, Ern Yu Ng, Kee Woei Loo, Joachim Say Chye |
| author_sort | Ho, Vincent H. B. |
| collection | NTU |
| description | Magnetic spheroid manipulation can be carried out in hanging drops to generate distinctly structured heterotypic microtissues through sequential addition of cells or spheroid to homotypic spheroids. These spheroids can also be incorporated in a droplet-based assay to screen for therapeutic efficacy in prolonged studies. This simple and versatile technique can offer potential benefits in tissue engineering and drug screening applications. |
| first_indexed | 2024-10-01T06:49:55Z |
| format | Journal Article |
| id | ntu-10356/83848 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T06:49:55Z |
| publishDate | 2016 |
| record_format | dspace |
| spelling | ntu-10356/838482020-06-01T10:13:54Z Manipulating Magnetic 3D Spheroids in Hanging Drops for Applications in Tissue Engineering and Drug Screening Ho, Vincent H. B. Guo, Wei Mei Huang, Charlotte L. Ho, Shu Fen Chaw, Su Yin Tan, Ern Yu Ng, Kee Woei Loo, Joachim Say Chye School of Materials Science & Engineering drug screening magnetic separation Magnetic spheroid manipulation can be carried out in hanging drops to generate distinctly structured heterotypic microtissues through sequential addition of cells or spheroid to homotypic spheroids. These spheroids can also be incorporated in a droplet-based assay to screen for therapeutic efficacy in prolonged studies. This simple and versatile technique can offer potential benefits in tissue engineering and drug screening applications. ASTAR (Agency for Sci., Tech. and Research, S’pore) NMRC (Natl Medical Research Council, S’pore) 2016-09-26T08:01:16Z 2019-12-06T15:33:10Z 2016-09-26T08:01:16Z 2019-12-06T15:33:10Z 2013 Journal Article Ho, V. H. B., Guo, W. M., Huang, C. L., Ho, S. F., Chaw, S. Y., Tan, E. Y., et al. (2013). Manipulating Magnetic 3D Spheroids in Hanging Drops for Applications in Tissue Engineering and Drug Screening. Advanced Healthcare Materials, 2(11), 1430-1434. 2192-2640 https://hdl.handle.net/10356/83848 http://hdl.handle.net/10220/41500 10.1002/adhm.201200408 en Advanced Healthcare Materials © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
| spellingShingle | drug screening magnetic separation Ho, Vincent H. B. Guo, Wei Mei Huang, Charlotte L. Ho, Shu Fen Chaw, Su Yin Tan, Ern Yu Ng, Kee Woei Loo, Joachim Say Chye Manipulating Magnetic 3D Spheroids in Hanging Drops for Applications in Tissue Engineering and Drug Screening |
| title | Manipulating Magnetic 3D Spheroids in Hanging Drops for Applications in Tissue Engineering and Drug Screening |
| title_full | Manipulating Magnetic 3D Spheroids in Hanging Drops for Applications in Tissue Engineering and Drug Screening |
| title_fullStr | Manipulating Magnetic 3D Spheroids in Hanging Drops for Applications in Tissue Engineering and Drug Screening |
| title_full_unstemmed | Manipulating Magnetic 3D Spheroids in Hanging Drops for Applications in Tissue Engineering and Drug Screening |
| title_short | Manipulating Magnetic 3D Spheroids in Hanging Drops for Applications in Tissue Engineering and Drug Screening |
| title_sort | manipulating magnetic 3d spheroids in hanging drops for applications in tissue engineering and drug screening |
| topic | drug screening magnetic separation |
| url | https://hdl.handle.net/10356/83848 http://hdl.handle.net/10220/41500 |
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