Progress in Understanding the Molecular Basis Underlying Functional Diversification of Cyclic Dinucleotide Turnover Proteins
Cyclic di-GMP was the first cyclic dinucleotide second messenger described, presaging the discovery of additional cyclic dinucleotide messengers in bacteria and eukaryotes. The GGDEF diguanylate cyclase (DGC) and EAL and HD-GYP phosphodiesterase (PDE) domains conduct the turnover of cyclic di-GMP. T...
Main Authors: | Römling, Ute, Liang, Zhao-Xun, Dow, J. Maxwell |
---|---|
Other Authors: | Margolin, William |
Format: | Journal Article |
Language: | English |
Published: |
2017
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/84161 http://hdl.handle.net/10220/43568 |
Similar Items
-
The Promise and Challenges of Cyclic Dinucleotides as Molecular Adjuvants for Vaccine Development
by: Hongbin Yan, et al.
Published: (2021-08-01) -
Exploration of the Binding Mechanism of Cyclic Dinucleotide Analogs to Stimulating Factor Proteins and the Implications for Subsequent Analog Drug Design
by: Shu-Wei Yuan, et al.
Published: (2024-03-01) -
Highly Efficient Preparation of Cyclic Dinucleotides via Engineering of Dinucleotide Cyclases in Escherichia coli
by: Yun Lv, et al.
Published: (2019-09-01) -
The Age of Cyclic Dinucleotide Vaccine Adjuvants
by: Himanshu Gogoi, et al.
Published: (2020-08-01) -
Structure and mechanism of a Hypr GGDEF enzyme that activates cGAMP signaling to control extracellular metal respiration
by: Zachary F Hallberg, et al.
Published: (2019-04-01)