In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives
A combined Lewis acid system comprising of two or more Lewis acids occasionally exhibits augmented catalytic activity in organic transformations which are otherwise unrealizable by either of the components exclusively. On the other hand, the efficient construction of multiple new C-C bonds and polyc...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2018
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| Online Access: | https://hdl.handle.net/10356/84294 http://hdl.handle.net/10220/45108 |
| _version_ | 1826125294619066368 |
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| author | Zhang, Qiu-Chi Zhang, Wen-Wei Shen, Liang Shen, Zhi-Liang Loh, Teck-Peng |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Zhang, Qiu-Chi Zhang, Wen-Wei Shen, Liang Shen, Zhi-Liang Loh, Teck-Peng |
| author_sort | Zhang, Qiu-Chi |
| collection | NTU |
| description | A combined Lewis acid system comprising of two or more Lewis acids occasionally exhibits augmented catalytic activity in organic transformations which are otherwise unrealizable by either of the components exclusively. On the other hand, the efficient construction of multiple new C-C bonds and polycyclic structures in minimal steps remains a subject of great interest in both academia and industry. Herein we report an efficient method to assemble aryldihydronaphthalene derivatives via a cascade reaction of diarylalkynes with acrylates under the catalysis of a combined Lewis acid derived from In(III) salt and TMSBr. |
| first_indexed | 2024-10-01T06:34:18Z |
| format | Journal Article |
| id | ntu-10356/84294 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T06:34:18Z |
| publishDate | 2018 |
| record_format | dspace |
| spelling | ntu-10356/842942023-02-28T19:31:18Z In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives Zhang, Qiu-Chi Zhang, Wen-Wei Shen, Liang Shen, Zhi-Liang Loh, Teck-Peng School of Physical and Mathematical Sciences Combined Lewis acid Indium A combined Lewis acid system comprising of two or more Lewis acids occasionally exhibits augmented catalytic activity in organic transformations which are otherwise unrealizable by either of the components exclusively. On the other hand, the efficient construction of multiple new C-C bonds and polycyclic structures in minimal steps remains a subject of great interest in both academia and industry. Herein we report an efficient method to assemble aryldihydronaphthalene derivatives via a cascade reaction of diarylalkynes with acrylates under the catalysis of a combined Lewis acid derived from In(III) salt and TMSBr. NRF (Natl Research Foundation, S’pore) MOE (Min. of Education, S’pore) Published version 2018-07-18T08:20:39Z 2019-12-06T15:42:16Z 2018-07-18T08:20:39Z 2019-12-06T15:42:16Z 2018 Journal Article Zhang, Q.-C., Zhang, W.-W., Shen, L., Shen, Z.-L., & Loh, T.-P. (2018). In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives. Molecules, 23(4), 979-. 1420-3049 https://hdl.handle.net/10356/84294 http://hdl.handle.net/10220/45108 10.3390/molecules23040979 en Molecules © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). 11 p. application/pdf |
| spellingShingle | Combined Lewis acid Indium Zhang, Qiu-Chi Zhang, Wen-Wei Shen, Liang Shen, Zhi-Liang Loh, Teck-Peng In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives |
| title | In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives |
| title_full | In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives |
| title_fullStr | In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives |
| title_full_unstemmed | In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives |
| title_short | In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives |
| title_sort | in iii tmsbr catalyzed cascade reaction of diarylalkynes with acrylates for the synthesis of aryldihydronaphthalene derivatives |
| topic | Combined Lewis acid Indium |
| url | https://hdl.handle.net/10356/84294 http://hdl.handle.net/10220/45108 |
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