Structural, Mechanical And Invitro Study On Pulsed Laser Deposition Of Hydroxyapatite On Additive Manufactured Substrate
The convergence of engineering and life science has evolved into a new paradigm called Bio Additive Manufacturing (BAM). This BAM encompasses the biofabrication using cells, biological or biomaterials as building blocks to fabricate biological and bio-application oriented substance, device and thera...
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| Other Authors: | |
| Format: | Conference Paper |
| Language: | English |
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2016
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| Online Access: | https://hdl.handle.net/10356/84578 http://hdl.handle.net/10220/41838 |
| _version_ | 1826119399816298496 |
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| author | Hariharan, K. Sugavaneswaran, M. Arumaikkannu, G. |
| author2 | Proceedings of the 2nd International Conference on Progress in Additive Manufacturing (Pro-AM 2016) |
| author_facet | Proceedings of the 2nd International Conference on Progress in Additive Manufacturing (Pro-AM 2016) Hariharan, K. Sugavaneswaran, M. Arumaikkannu, G. |
| author_sort | Hariharan, K. |
| collection | NTU |
| description | The convergence of engineering and life science has evolved into a new paradigm called Bio Additive Manufacturing (BAM). This BAM encompasses the biofabrication using cells, biological or biomaterials as building blocks to fabricate biological and bio-application oriented substance, device and therapeutic products through a broad range of engineering and biological processes. Furthermore bioactive coating on BAM surface facilitates biological fixation between the prosthesis and the hard tissue which increases the long term stability and integrity of the implant. In this paper, Hydroxyapatite (HA) Powder was coated over Additive Manufactured polyamide substrate using Pulsed Laser Deposition. Coating Morphology was characterized using SEM analysis and observed that the coating was dominated by the presence of particle droplet with different size. Compounds like tricalcium phosphate and few amorphous calcium phosphate were found along with HA which was confirmed by XRD analysis. Nano-indentation and pull-out test reveals that the layer was strong enough and withstands higher load before it peels-off. Cell line study has been carried out with MG-63 Osteosarcoma cells and results showed that the cells on coated surface multiplied better than on uncoated surface. It was evident from the results, that this kind of coating favors the long-term stability of implant fabricated using Additive Manufacturing. |
| first_indexed | 2024-10-01T04:59:41Z |
| format | Conference Paper |
| id | ntu-10356/84578 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T04:59:41Z |
| publishDate | 2016 |
| record_format | dspace |
| spelling | ntu-10356/845782020-09-24T20:12:17Z Structural, Mechanical And Invitro Study On Pulsed Laser Deposition Of Hydroxyapatite On Additive Manufactured Substrate Hariharan, K. Sugavaneswaran, M. Arumaikkannu, G. Proceedings of the 2nd International Conference on Progress in Additive Manufacturing (Pro-AM 2016) Singapore Centre for 3D Printing BioAdditive Manufacturing Hydroxyapatite The convergence of engineering and life science has evolved into a new paradigm called Bio Additive Manufacturing (BAM). This BAM encompasses the biofabrication using cells, biological or biomaterials as building blocks to fabricate biological and bio-application oriented substance, device and therapeutic products through a broad range of engineering and biological processes. Furthermore bioactive coating on BAM surface facilitates biological fixation between the prosthesis and the hard tissue which increases the long term stability and integrity of the implant. In this paper, Hydroxyapatite (HA) Powder was coated over Additive Manufactured polyamide substrate using Pulsed Laser Deposition. Coating Morphology was characterized using SEM analysis and observed that the coating was dominated by the presence of particle droplet with different size. Compounds like tricalcium phosphate and few amorphous calcium phosphate were found along with HA which was confirmed by XRD analysis. Nano-indentation and pull-out test reveals that the layer was strong enough and withstands higher load before it peels-off. Cell line study has been carried out with MG-63 Osteosarcoma cells and results showed that the cells on coated surface multiplied better than on uncoated surface. It was evident from the results, that this kind of coating favors the long-term stability of implant fabricated using Additive Manufacturing. Published version 2016-12-13T07:48:46Z 2019-12-06T15:47:37Z 2016-12-13T07:48:46Z 2019-12-06T15:47:37Z 2016 Conference Paper Hariharan, K., Sugavaneswaran, M., & Arumaikkannu, G. (2016). Structural, Mechanical And Invitro Study On Pulsed Laser Deposition Of Hydroxyapatite On Additive Manufactured Substrate. Proceedings of the 2nd International Conference on Progress in Additive Manufacturing (Pro-AM 2016), 146-151. https://hdl.handle.net/10356/84578 http://hdl.handle.net/10220/41838 en © 2016 by Pro-AM 2016 Organizers. Published by Research Publishing, Singapore 6 p. application/pdf |
| spellingShingle | BioAdditive Manufacturing Hydroxyapatite Hariharan, K. Sugavaneswaran, M. Arumaikkannu, G. Structural, Mechanical And Invitro Study On Pulsed Laser Deposition Of Hydroxyapatite On Additive Manufactured Substrate |
| title | Structural, Mechanical And Invitro Study On Pulsed Laser Deposition Of Hydroxyapatite On Additive Manufactured Substrate |
| title_full | Structural, Mechanical And Invitro Study On Pulsed Laser Deposition Of Hydroxyapatite On Additive Manufactured Substrate |
| title_fullStr | Structural, Mechanical And Invitro Study On Pulsed Laser Deposition Of Hydroxyapatite On Additive Manufactured Substrate |
| title_full_unstemmed | Structural, Mechanical And Invitro Study On Pulsed Laser Deposition Of Hydroxyapatite On Additive Manufactured Substrate |
| title_short | Structural, Mechanical And Invitro Study On Pulsed Laser Deposition Of Hydroxyapatite On Additive Manufactured Substrate |
| title_sort | structural mechanical and invitro study on pulsed laser deposition of hydroxyapatite on additive manufactured substrate |
| topic | BioAdditive Manufacturing Hydroxyapatite |
| url | https://hdl.handle.net/10356/84578 http://hdl.handle.net/10220/41838 |
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