The humanistic and economic burden of chronic wounds: a protocol for a systematic review
Background: Chronic non-healing wounds present a substantial economic burden to healthcare system; significant reductions in quality of life for those affected, and precede often serious events such as limp amputations or even premature deaths. This burden is also likely to increase with a larger pr...
| Main Authors: | , , , , , , |
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| Format: | Journal Article |
| Language: | English |
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2017
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| Online Access: | https://hdl.handle.net/10356/84977 http://hdl.handle.net/10220/42078 |
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| author | Schmidtchen, Artur Pang, Caroline Bajpai, Ram Järbrink, Krister Ni, Gao Sönnergren, Henrik Car, Josip |
| author2 | Lee Kong Chian School of Medicine (LKCMedicine) |
| author_facet | Lee Kong Chian School of Medicine (LKCMedicine) Schmidtchen, Artur Pang, Caroline Bajpai, Ram Järbrink, Krister Ni, Gao Sönnergren, Henrik Car, Josip |
| author_sort | Schmidtchen, Artur |
| collection | NTU |
| description | Background: Chronic non-healing wounds present a substantial economic burden to healthcare system; significant reductions in quality of life for those affected, and precede often serious events such as limp amputations or even premature deaths. This burden is also likely to increase with a larger proportion of elderly and increasing prevalence of life-style diseases such as obesity and diabetes. Reviews of the evidence on the burden of illness associated with chronic wounds have not been comprehensive in scope and have not provided an assessment of the distribution of the health care costs across categories of resource use. Methods/design: This study is a systematic review of multiple databases for studies on adult patients with chronic wounds and with the primary objective to assess the impact on health-related quality of life by category of ulcers, and associated direct and indirect costs. Eligible studies will primary be empirical studies evaluating, describing or comparing measurement of quality of life and economic impact. Two reviewers will independently screen titles and abstracts and select studies involving adults with chronic wounds. These investigators will also independently extract data using a pre-designed data extraction form. Differences in applied methodologies and uncertainties will clearly be accounted for. Conservative valuations of costs and impact on health-related quality of life will be prioritised. Variations that may depend on age distribution, the categorisation of ulcer, healthcare system etc. will be described clearly. Discussion: The proposed systematic review will yield a comprehensive assessment of the humanistic and economic burden of chronic wounds in an adult population. A better understanding of the humanistic and economic burden of chronic wounds is essential for policy and planning purposes, to monitor trends in disease burden and not at least in order to estimate the real-world cost-effectiveness of new treatments and therapies. Systematic review registration: PROSPERO CRD42016037496. |
| first_indexed | 2024-10-01T02:55:28Z |
| format | Journal Article |
| id | ntu-10356/84977 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T02:55:28Z |
| publishDate | 2017 |
| record_format | dspace |
| spelling | ntu-10356/849772020-11-01T05:12:27Z The humanistic and economic burden of chronic wounds: a protocol for a systematic review Schmidtchen, Artur Pang, Caroline Bajpai, Ram Järbrink, Krister Ni, Gao Sönnergren, Henrik Car, Josip Lee Kong Chian School of Medicine (LKCMedicine) Hard-to-heal ulcers Chronic wounds Background: Chronic non-healing wounds present a substantial economic burden to healthcare system; significant reductions in quality of life for those affected, and precede often serious events such as limp amputations or even premature deaths. This burden is also likely to increase with a larger proportion of elderly and increasing prevalence of life-style diseases such as obesity and diabetes. Reviews of the evidence on the burden of illness associated with chronic wounds have not been comprehensive in scope and have not provided an assessment of the distribution of the health care costs across categories of resource use. Methods/design: This study is a systematic review of multiple databases for studies on adult patients with chronic wounds and with the primary objective to assess the impact on health-related quality of life by category of ulcers, and associated direct and indirect costs. Eligible studies will primary be empirical studies evaluating, describing or comparing measurement of quality of life and economic impact. Two reviewers will independently screen titles and abstracts and select studies involving adults with chronic wounds. These investigators will also independently extract data using a pre-designed data extraction form. Differences in applied methodologies and uncertainties will clearly be accounted for. Conservative valuations of costs and impact on health-related quality of life will be prioritised. Variations that may depend on age distribution, the categorisation of ulcer, healthcare system etc. will be described clearly. Discussion: The proposed systematic review will yield a comprehensive assessment of the humanistic and economic burden of chronic wounds in an adult population. A better understanding of the humanistic and economic burden of chronic wounds is essential for policy and planning purposes, to monitor trends in disease burden and not at least in order to estimate the real-world cost-effectiveness of new treatments and therapies. Systematic review registration: PROSPERO CRD42016037496. ASTAR (Agency for Sci., Tech. and Research, S’pore) Published version 2017-02-09T08:39:44Z 2019-12-06T15:54:45Z 2017-02-09T08:39:44Z 2019-12-06T15:54:45Z 2017 Journal Article Järbrink, K., Ni, G., Sönnergren, H., Schmidtchen, A., Pang, C., Bajpai, R., et al. (2017). The humanistic and economic burden of chronic wounds: a protocol for a systematic review. Systematic Reviews, 6, 15-. 2046-4053 https://hdl.handle.net/10356/84977 http://hdl.handle.net/10220/42078 10.1186/s13643-016-0400-8 en Systematic Reviews © 2017 The Author(s). This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. 7 p. application/pdf |
| spellingShingle | Hard-to-heal ulcers Chronic wounds Schmidtchen, Artur Pang, Caroline Bajpai, Ram Järbrink, Krister Ni, Gao Sönnergren, Henrik Car, Josip The humanistic and economic burden of chronic wounds: a protocol for a systematic review |
| title | The humanistic and economic burden of chronic wounds: a protocol for a systematic review |
| title_full | The humanistic and economic burden of chronic wounds: a protocol for a systematic review |
| title_fullStr | The humanistic and economic burden of chronic wounds: a protocol for a systematic review |
| title_full_unstemmed | The humanistic and economic burden of chronic wounds: a protocol for a systematic review |
| title_short | The humanistic and economic burden of chronic wounds: a protocol for a systematic review |
| title_sort | humanistic and economic burden of chronic wounds a protocol for a systematic review |
| topic | Hard-to-heal ulcers Chronic wounds |
| url | https://hdl.handle.net/10356/84977 http://hdl.handle.net/10220/42078 |
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