Performance Characterization of a Switchable Acoustic Resolution and Optical Resolution Photoacoustic Microscopy System
Photoacoustic microscopy (PAM) is a scalable bioimaging modality; one can choose low acoustic resolution with deep penetration depth or high optical resolution with shallow imaging depth. High spatial resolution and deep penetration depth is rather difficult to achieve using a single system. Here we...
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
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2017
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| Online Access: | https://hdl.handle.net/10356/85011 http://hdl.handle.net/10220/42090 http://www.mdpi.com/1424-8220/17/2/357 |
| _version_ | 1826119088357769216 |
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| author | Moothanchery, Mohesh Pramanik, Manojit |
| author2 | School of Chemical and Biomedical Engineering |
| author_facet | School of Chemical and Biomedical Engineering Moothanchery, Mohesh Pramanik, Manojit |
| author_sort | Moothanchery, Mohesh |
| collection | NTU |
| description | Photoacoustic microscopy (PAM) is a scalable bioimaging modality; one can choose low acoustic resolution with deep penetration depth or high optical resolution with shallow imaging depth. High spatial resolution and deep penetration depth is rather difficult to achieve using a single system. Here we report a switchable acoustic resolution and optical resolution photoacoustic microscopy (AR-OR-PAM) system in a single imaging system capable of both high resolution and low resolution on the same sample. Lateral resolution of 4.2 µm (with ~1.4 mm imaging depth) and lateral resolution of 45 μm (with ~7.6 mm imaging depth) was successfully demonstrated using a switchable system. In vivo blood vasculature imaging was also performed for its biological application. |
| first_indexed | 2024-10-01T04:54:20Z |
| format | Journal Article |
| id | ntu-10356/85011 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T04:54:20Z |
| publishDate | 2017 |
| record_format | dspace |
| spelling | ntu-10356/850112023-12-29T06:48:24Z Performance Characterization of a Switchable Acoustic Resolution and Optical Resolution Photoacoustic Microscopy System Moothanchery, Mohesh Pramanik, Manojit School of Chemical and Biomedical Engineering Photoacoustic imaging AR-PAM Photoacoustic microscopy (PAM) is a scalable bioimaging modality; one can choose low acoustic resolution with deep penetration depth or high optical resolution with shallow imaging depth. High spatial resolution and deep penetration depth is rather difficult to achieve using a single system. Here we report a switchable acoustic resolution and optical resolution photoacoustic microscopy (AR-OR-PAM) system in a single imaging system capable of both high resolution and low resolution on the same sample. Lateral resolution of 4.2 µm (with ~1.4 mm imaging depth) and lateral resolution of 45 μm (with ~7.6 mm imaging depth) was successfully demonstrated using a switchable system. In vivo blood vasculature imaging was also performed for its biological application. MOE (Min. of Education, S’pore) Published version 2017-02-13T02:55:38Z 2019-12-06T15:55:27Z 2017-02-13T02:55:38Z 2019-12-06T15:55:27Z 2017 2017 Journal Article Moothanchery, M., & Pramanik, M. (2017). Performance Characterization of a Switchable Acoustic Resolution and Optical Resolution Photoacoustic Microscopy System. Sensors, 17(2), 357-. 1424-8220 https://hdl.handle.net/10356/85011 http://hdl.handle.net/10220/42090 http://www.mdpi.com/1424-8220/17/2/357 195987 en Sensors © 2017 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). 11 p. application/pdf |
| spellingShingle | Photoacoustic imaging AR-PAM Moothanchery, Mohesh Pramanik, Manojit Performance Characterization of a Switchable Acoustic Resolution and Optical Resolution Photoacoustic Microscopy System |
| title | Performance Characterization of a Switchable Acoustic Resolution and Optical Resolution Photoacoustic Microscopy System |
| title_full | Performance Characterization of a Switchable Acoustic Resolution and Optical Resolution Photoacoustic Microscopy System |
| title_fullStr | Performance Characterization of a Switchable Acoustic Resolution and Optical Resolution Photoacoustic Microscopy System |
| title_full_unstemmed | Performance Characterization of a Switchable Acoustic Resolution and Optical Resolution Photoacoustic Microscopy System |
| title_short | Performance Characterization of a Switchable Acoustic Resolution and Optical Resolution Photoacoustic Microscopy System |
| title_sort | performance characterization of a switchable acoustic resolution and optical resolution photoacoustic microscopy system |
| topic | Photoacoustic imaging AR-PAM |
| url | https://hdl.handle.net/10356/85011 http://hdl.handle.net/10220/42090 http://www.mdpi.com/1424-8220/17/2/357 |
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