Thermal diffusivity variations in nanoparticle administered phantom tissues : a photoacoustic investigation
Gold nanoparticles have great potential toward optical investigations in biological tissues which include imaging applications as well as therapeutic applications. However, introduction of gold nanoparticles such as nanospheres into the tissue may alter the inherent physical properties of the embedd...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/85687 http://hdl.handle.net/10220/16256 |
| _version_ | 1826115334414794752 |
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| author | Joseph, J. Sathiyamoorthy, K. Murukeshan, V. M. Woh, L. S. |
| author2 | School of Mechanical and Aerospace Engineering |
| author_facet | School of Mechanical and Aerospace Engineering Joseph, J. Sathiyamoorthy, K. Murukeshan, V. M. Woh, L. S. |
| author_sort | Joseph, J. |
| collection | NTU |
| description | Gold nanoparticles have great potential toward optical investigations in biological tissues which include imaging applications as well as therapeutic applications. However, introduction of gold nanoparticles such as nanospheres into the tissue may alter the inherent physical properties of the embedding medium. Of note, the thermal diffusivity of the medium will be significantly altered imposing serious limitations to the efficacy of several imaging and therapeutic modalities. In this context, we report experimental investigations based on open photoacoustic cell configuration to evaluate the thermal diffusivity changes in polyvinyl alcohol (PVA) phantom tissue doped with gold nanospheres. The investigations performed demonstrate a non-destructive methodology for the measurement of thermal diffusivity and the experimental results show that the thermal diffusivity of the tissue will be significantly reduced when they are administered with plasmonic nanoparticles. |
| first_indexed | 2024-10-01T03:53:46Z |
| format | Journal Article |
| id | ntu-10356/85687 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T03:53:46Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | ntu-10356/856872020-03-07T13:19:25Z Thermal diffusivity variations in nanoparticle administered phantom tissues : a photoacoustic investigation Joseph, J. Sathiyamoorthy, K. Murukeshan, V. M. Woh, L. S. School of Mechanical and Aerospace Engineering DRNTU::Engineering::Mechanical engineering Gold nanoparticles have great potential toward optical investigations in biological tissues which include imaging applications as well as therapeutic applications. However, introduction of gold nanoparticles such as nanospheres into the tissue may alter the inherent physical properties of the embedding medium. Of note, the thermal diffusivity of the medium will be significantly altered imposing serious limitations to the efficacy of several imaging and therapeutic modalities. In this context, we report experimental investigations based on open photoacoustic cell configuration to evaluate the thermal diffusivity changes in polyvinyl alcohol (PVA) phantom tissue doped with gold nanospheres. The investigations performed demonstrate a non-destructive methodology for the measurement of thermal diffusivity and the experimental results show that the thermal diffusivity of the tissue will be significantly reduced when they are administered with plasmonic nanoparticles. 2013-10-04T04:06:50Z 2019-12-06T16:08:18Z 2013-10-04T04:06:50Z 2019-12-06T16:08:18Z 2012 2012 Journal Article Joseph, J., Sathiyamoorthy, K., Murukeshan, V. M., & Woh, L. S. (2012). Thermal diffusivity variations in nanoparticle administered phantom tissues : a photoacoustic investigation. The European physical journal applied physics, 59(3). https://hdl.handle.net/10356/85687 http://hdl.handle.net/10220/16256 10.1051/epjap/2012120060 en The European physical journal applied physics |
| spellingShingle | DRNTU::Engineering::Mechanical engineering Joseph, J. Sathiyamoorthy, K. Murukeshan, V. M. Woh, L. S. Thermal diffusivity variations in nanoparticle administered phantom tissues : a photoacoustic investigation |
| title | Thermal diffusivity variations in nanoparticle administered phantom tissues : a photoacoustic investigation |
| title_full | Thermal diffusivity variations in nanoparticle administered phantom tissues : a photoacoustic investigation |
| title_fullStr | Thermal diffusivity variations in nanoparticle administered phantom tissues : a photoacoustic investigation |
| title_full_unstemmed | Thermal diffusivity variations in nanoparticle administered phantom tissues : a photoacoustic investigation |
| title_short | Thermal diffusivity variations in nanoparticle administered phantom tissues : a photoacoustic investigation |
| title_sort | thermal diffusivity variations in nanoparticle administered phantom tissues a photoacoustic investigation |
| topic | DRNTU::Engineering::Mechanical engineering |
| url | https://hdl.handle.net/10356/85687 http://hdl.handle.net/10220/16256 |
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