Inhibition of NLRP3 inflammasome activation by cell-permeable stapled peptides
Interleukin-1β (IL-1β) is a major cytokine that initiates and enhances inflammatory responses. Excessive IL-1β production is a characteristic of most chronic inflammatory diseases, including atherosclerosis, type 2 diabetes, and obesity, which affect a large proportion of the global population. The...
Main Authors: | Verma, Chandra Shekhar, Lane, David P., Mortellaro, Alessandra, Pal, Arumay, Neo, Kurt, Rajamani, Lakshminarayanan, Ferrer, Fernando Jose |
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Other Authors: | School of Biological Sciences |
Format: | Journal Article |
Language: | English |
Published: |
2019
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/85928 http://hdl.handle.net/10220/48277 |
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