Thrombin-derived host defence peptide modulates neutrophil rolling and migration in vitro and functional response in vivo
Host defence peptides (HDPs) derived from the C-terminus of thrombin are proteolytically generated by enzymes released during inflammation and wounding. In this work, we studied the effects of the prototypic peptide GKY25 (GKYGFYTHVFRLKKWIQKVIDQFGE), on neutrophil functions. In vitro, GKY25 was show...
Main Authors: | Lim, Chun Hwee, Puthia, Manoj, Butrym, Marta, Tay, Hui Min, Lee, Michelle Zi Yi, Hou, Han Wei, Schmidtchen, Artur |
---|---|
Other Authors: | Interdisciplinary Graduate School (IGS) |
Format: | Journal Article |
Language: | English |
Published: |
2017
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/86509 http://hdl.handle.net/10220/44087 |
Similar Items
-
Thrombin and plasmin alter the proteome of neutrophil extracellular traps
by: Lim, Chun Hwee, et al.
Published: (2018) -
The Regulation of Neutrophil Migration in Patients with Sepsis: The Complexity of the Molecular Mechanisms and Their Modulation in Sepsis and the Heterogeneity of Sepsis Patients
by: Øystein Bruserud, et al.
Published: (2023-03-01) -
Failure of neutrophil migration toward infectious focus in severe sepsis: a critical event for the outcome of this syndrome
by: José Carlos Alves-Filho, et al.
Published: (2005-03-01) -
Neutrophil, neutrophil extracellular traps and endothelial cell dysfunction in sepsis
by: Hao Zhang, et al.
Published: (2023-01-01) -
Toxic granules in neutrophils in sepsis patients: Does it really helpful?
by: Subhash Chander, et al.
Published: (2023-01-01)