Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody 513

Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody 513

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Dengue is a widespread viral disease with 3.6 billion people at risk worldwide. Humanized monoclonal antibody (mAb) 513, currently undergoing clinical trials in Singapore, targets an epitope on the envelope protein domain III exposed at the surface of the viral particle. This antibody potently neutr...

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Bibliographic Details
Main Authors: Wong, Yee Hwa, Kumar, Akshita, Liew, Chong Wai, Tharakaraman, Kannan, Srinivasaraghavan, Kannan, Sasisekharan, Ram, Verma, Chandra, Lescar, Julien
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2018
Subjects:
Dengue Virus
Humanized Monoclonal Antibody 513
Online Access:https://hdl.handle.net/10356/86830
http://hdl.handle.net/10220/45324

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