LIM kinase1 regulates mitotic centrosome integrity via its activity on dynein light intermediate chains

Abnormal centrosome number and function have been implicated in tumour development. LIM kinase1 (LIMK1), a regulator of actin cytoskeleton dynamics, is found to localize at the mitotic centrosome. However, its role at the centrosome is not fully explored. Here, we report that LIMK1 depletion resulte...

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Bibliographic Details
Main Authors: Ou, Sirong, Tan, Mei-Hua, Weng, Ting, Li, HoiYeung, Koh, Cheng-Gee
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/86849
http://hdl.handle.net/10220/45334