Global H3.3 dynamic deposition defines its bimodal role in cell fate transition

Global H3.3 dynamic deposition defines its bimodal role in cell fate transition

H3.3 is a histone variant, which is deposited on genebodies and regulatory elements, by Hira, marking active transcription. Moreover, H3.3 is deposited on heterochromatin by Atrx/Daxx complex. The exact role of H3.3 in cell fate transition remains elusive. Here, we investigate the dynamic changes in...

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Bibliographic Details
Main Authors: Fang, Hai-Tong, EL Farran, Chadi A., Xing, Qiao Rui, Zhang, Li-Feng, Li, Hu, Lim, Bing, Loh, Yuin-Han
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2018
Subjects:
Dynamic Deposition
Cell Fate Transition
Online Access:https://hdl.handle.net/10356/87038
http://hdl.handle.net/10220/45296

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