Cupula-Inspired Hyaluronic Acid-Based Hydrogel Encapsulation to Form Biomimetic MEMS Flow Sensors
Blind cavefishes are known to detect objects through hydrodynamic vision enabled by arrays of biological flow sensors called neuromasts. This work demonstrates the development of a MEMS artificial neuromast sensor that features a 3D polymer hair cell that extends into the ambient flow. The hair cell...
| Main Authors: | , , , , , |
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| Format: | Journal Article |
| Language: | English |
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2018
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| Online Access: | https://hdl.handle.net/10356/87068 http://hdl.handle.net/10220/44274 |
| _version_ | 1826114719513051136 |
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| author | Kottapalli, Ajay Giri Prakash Bora, Meghali Kanhere, Elgar Asadnia, Mohsen Miao, Jianmin Triantafyllou, Michael S. |
| author2 | School of Mechanical and Aerospace Engineering |
| author_facet | School of Mechanical and Aerospace Engineering Kottapalli, Ajay Giri Prakash Bora, Meghali Kanhere, Elgar Asadnia, Mohsen Miao, Jianmin Triantafyllou, Michael S. |
| author_sort | Kottapalli, Ajay Giri Prakash |
| collection | NTU |
| description | Blind cavefishes are known to detect objects through hydrodynamic vision enabled by arrays of biological flow sensors called neuromasts. This work demonstrates the development of a MEMS artificial neuromast sensor that features a 3D polymer hair cell that extends into the ambient flow. The hair cell is monolithically fabricated at the center of a 2 μm thick silicon membrane that is photo-patterned with a full-bridge bias circuit. Ambient flow variations exert a drag force on the hair cell, which causes a displacement of the sensing membrane. This in turn leads to the resistance imbalance in the bridge circuit generating a voltage output. Inspired by the biological neuromast, a biomimetic synthetic hydrogel cupula is incorporated on the hair cell. The morphology, swelling behavior, porosity and mechanical properties of the hyaluronic acid hydrogel are characterized through rheology and nanoindentation techniques. The sensitivity enhancement in the sensor output due to the material and mechanical contributions of the micro-porous hydrogel cupula is investigated through experiments. |
| first_indexed | 2024-10-01T03:43:44Z |
| format | Journal Article |
| id | ntu-10356/87068 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T03:43:44Z |
| publishDate | 2018 |
| record_format | dspace |
| spelling | ntu-10356/870682023-03-04T17:13:24Z Cupula-Inspired Hyaluronic Acid-Based Hydrogel Encapsulation to Form Biomimetic MEMS Flow Sensors Kottapalli, Ajay Giri Prakash Bora, Meghali Kanhere, Elgar Asadnia, Mohsen Miao, Jianmin Triantafyllou, Michael S. School of Mechanical and Aerospace Engineering Singapore-MIT Alliance Programme Biomimetic Sensors Hydrogels Blind cavefishes are known to detect objects through hydrodynamic vision enabled by arrays of biological flow sensors called neuromasts. This work demonstrates the development of a MEMS artificial neuromast sensor that features a 3D polymer hair cell that extends into the ambient flow. The hair cell is monolithically fabricated at the center of a 2 μm thick silicon membrane that is photo-patterned with a full-bridge bias circuit. Ambient flow variations exert a drag force on the hair cell, which causes a displacement of the sensing membrane. This in turn leads to the resistance imbalance in the bridge circuit generating a voltage output. Inspired by the biological neuromast, a biomimetic synthetic hydrogel cupula is incorporated on the hair cell. The morphology, swelling behavior, porosity and mechanical properties of the hyaluronic acid hydrogel are characterized through rheology and nanoindentation techniques. The sensitivity enhancement in the sensor output due to the material and mechanical contributions of the micro-porous hydrogel cupula is investigated through experiments. NRF (Natl Research Foundation, S’pore) Published version 2018-01-08T09:03:04Z 2019-12-06T16:34:27Z 2018-01-08T09:03:04Z 2019-12-06T16:34:27Z 2017 Journal Article Kottapalli, A. G. P., Bora, M., Kanhere, E., Asadnia, M., Miao, J., & Triantafyllou, M. S. (2017). Cupula-Inspired Hyaluronic Acid-Based Hydrogel Encapsulation to Form Biomimetic MEMS Flow Sensors. Sensors, 17(8), 1728-. 1424-8220 https://hdl.handle.net/10356/87068 http://hdl.handle.net/10220/44274 10.3390/s17081728 en Sensors © 2017 by The Author(s). Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). 14 p. application/pdf |
| spellingShingle | Biomimetic Sensors Hydrogels Kottapalli, Ajay Giri Prakash Bora, Meghali Kanhere, Elgar Asadnia, Mohsen Miao, Jianmin Triantafyllou, Michael S. Cupula-Inspired Hyaluronic Acid-Based Hydrogel Encapsulation to Form Biomimetic MEMS Flow Sensors |
| title | Cupula-Inspired Hyaluronic Acid-Based Hydrogel Encapsulation to Form Biomimetic MEMS Flow Sensors |
| title_full | Cupula-Inspired Hyaluronic Acid-Based Hydrogel Encapsulation to Form Biomimetic MEMS Flow Sensors |
| title_fullStr | Cupula-Inspired Hyaluronic Acid-Based Hydrogel Encapsulation to Form Biomimetic MEMS Flow Sensors |
| title_full_unstemmed | Cupula-Inspired Hyaluronic Acid-Based Hydrogel Encapsulation to Form Biomimetic MEMS Flow Sensors |
| title_short | Cupula-Inspired Hyaluronic Acid-Based Hydrogel Encapsulation to Form Biomimetic MEMS Flow Sensors |
| title_sort | cupula inspired hyaluronic acid based hydrogel encapsulation to form biomimetic mems flow sensors |
| topic | Biomimetic Sensors Hydrogels |
| url | https://hdl.handle.net/10356/87068 http://hdl.handle.net/10220/44274 |
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