Feeding Angptl4 −/− mice trans fat promotes foam cell formation in mesenteric lymph nodes without leading to ascites

Feeding Angptl4 −/− mice trans fat promotes foam cell formation in mesenteric lymph nodes without leading to ascites

Angiopoietin-like 4 (ANGPTL4) regulates plasma triglyceride levels by inhibiting LPL. Inactivation of ANGPTL4 decreases plasma triglycerides and reduces the risk of coronary artery disease. Unfortunately, targeting ANGPTL4 for the therapeutic management of dyslipidemia and atherosclerosis is hampere...

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Bibliographic Details
Main Authors: Oteng, Antwi-Boasiako, Bhattacharya, Asmita, Brodesser, Susanne, Qi, Ling, Tan, Nguan Soon, Kersten, Sander
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2018
Subjects:
Inflammation
Lipotoxicity
Online Access:https://hdl.handle.net/10356/87195
http://hdl.handle.net/10220/44365

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