Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems
Significant progress on upconversion-nanoparticle (UCNP)-based probes is witnessed in recent years. Compared with traditional fluorescent probes (e.g., organic dyes, metal complexes, or inorganic quantum dots), UCNPs have many advantages such as non-autofluorescence, high chemical stability, large l...
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| Format: | Journal Article |
| Language: | English |
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2018
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| Online Access: | https://hdl.handle.net/10356/87265 http://hdl.handle.net/10220/44379 |
| _version_ | 1824455727162327040 |
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| author | Gu, Bin Zhang, Qichun |
| author2 | School of Materials Science & Engineering |
| author_facet | School of Materials Science & Engineering Gu, Bin Zhang, Qichun |
| author_sort | Gu, Bin |
| collection | NTU |
| description | Significant progress on upconversion-nanoparticle (UCNP)-based probes is witnessed in recent years. Compared with traditional fluorescent probes (e.g., organic dyes, metal complexes, or inorganic quantum dots), UCNPs have many advantages such as non-autofluorescence, high chemical stability, large light-penetration depth, long lifetime, and less damage to samples. This article focuses on recent achievements in the usage of lanthanide-doped UCNPs as efficient probes for biodetection since 2014. The mechanisms of upconversion as well as the luminescence resonance energy transfer process is introduced first, followed by a detailed summary on the recent researches of UCNP-based biodetections including the detection of inorganic ions, gas molecules, reactive oxygen species, and thiols and hydrogen sulfide. |
| first_indexed | 2025-02-19T03:42:48Z |
| format | Journal Article |
| id | ntu-10356/87265 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2025-02-19T03:42:48Z |
| publishDate | 2018 |
| record_format | dspace |
| spelling | ntu-10356/872652023-02-28T19:21:44Z Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems Gu, Bin Zhang, Qichun School of Materials Science & Engineering School of Physical and Mathematical Sciences Upconversion Small Molecules Significant progress on upconversion-nanoparticle (UCNP)-based probes is witnessed in recent years. Compared with traditional fluorescent probes (e.g., organic dyes, metal complexes, or inorganic quantum dots), UCNPs have many advantages such as non-autofluorescence, high chemical stability, large light-penetration depth, long lifetime, and less damage to samples. This article focuses on recent achievements in the usage of lanthanide-doped UCNPs as efficient probes for biodetection since 2014. The mechanisms of upconversion as well as the luminescence resonance energy transfer process is introduced first, followed by a detailed summary on the recent researches of UCNP-based biodetections including the detection of inorganic ions, gas molecules, reactive oxygen species, and thiols and hydrogen sulfide. MOE (Min. of Education, S’pore) Published version 2018-02-02T03:41:17Z 2019-12-06T16:38:29Z 2018-02-02T03:41:17Z 2019-12-06T16:38:29Z 2018 Journal Article Gu, B., & Zhang, Q. (2018). Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems. Advanced Science, 5(3), 1700609-. https://hdl.handle.net/10356/87265 http://hdl.handle.net/10220/44379 10.1002/advs.201700609 en Advanced Science © 2018 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and re-production in any medium, provided the original work is properly cited. 16 p. application/pdf |
| spellingShingle | Upconversion Small Molecules Gu, Bin Zhang, Qichun Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems |
| title | Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems |
| title_full | Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems |
| title_fullStr | Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems |
| title_full_unstemmed | Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems |
| title_short | Recent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems |
| title_sort | recent advances on functionalized upconversion nanoparticles for detection of small molecules and ions in biosystems |
| topic | Upconversion Small Molecules |
| url | https://hdl.handle.net/10356/87265 http://hdl.handle.net/10220/44379 |
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