NLRP10 Enhances CD4+ T-Cell-Mediated IFNγ Response via Regulation of Dendritic Cell-Derived IL-12 Release

NLRP10 Enhances CD4+ T-Cell-Mediated IFNγ Response via Regulation of Dendritic Cell-Derived IL-12 Release

NLRP10 is a nucleotide-binding oligomerization domain-like receptor that functions as an intracellular pattern recognition receptor for microbial products. Here, we generated a Nlrp10−/− mouse to delineate the role of NLRP10 in the host immune response and found that Nlrp10−/− dendritic cells (DCs)...

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Bibliographic Details
Main Authors: Vacca, Maurizio, Böhme, Julia, Zambetti, Lia Paola, Khameneh, Hanif Javanmard, Paleja, Bhairav S., Laudisi, Federica, Ho, Adrian W. S., Neo, Kurt, Leong, Keith Weng Kit, Marzuki, Mardiana, Lee, Bernett, Poidinger, Michael, Santambrogio, Laura, Tsenova, Liana, Zolezzi, Francesca, De Libero, Gennaro, Singhal, Amit, Mortellaro, Alessandra
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2018
Subjects:
Mycobacterium Tuberculosis
Dendritic Cells
Online Access:https://hdl.handle.net/10356/87419
http://hdl.handle.net/10220/44459

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