Identification of antibacterial components in human hair shafts

Antimicrobial peptides (AMPs) are evolutionarily old components of innate immunity. AMPs identified in human skin include defensins, cathelicidin, dermcidin, psoriasin, and RNase7 (1, 2). Some AMPs, such as the human cathelicidin peptide LL-37, are upregulated during inflammation in skin (1). Variou...

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Main Authors: Subbaiah, Roopa S., Kerk, Swat Kim, Lian, Yilong, Lunny, Declan, Sze, Siu Kwan, Ng, Kee Woei, Schmidtchen, Artur, Adav, Sunil Shankar
Other Authors: School of Materials Science & Engineering
Format: Journal Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/87924
http://hdl.handle.net/10220/45603
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author Subbaiah, Roopa S.
Kerk, Swat Kim
Lian, Yilong
Lunny, Declan
Sze, Siu Kwan
Ng, Kee Woei
Schmidtchen, Artur
Adav, Sunil Shankar
author2 School of Materials Science & Engineering
author_facet School of Materials Science & Engineering
Subbaiah, Roopa S.
Kerk, Swat Kim
Lian, Yilong
Lunny, Declan
Sze, Siu Kwan
Ng, Kee Woei
Schmidtchen, Artur
Adav, Sunil Shankar
author_sort Subbaiah, Roopa S.
collection NTU
description Antimicrobial peptides (AMPs) are evolutionarily old components of innate immunity. AMPs identified in human skin include defensins, cathelicidin, dermcidin, psoriasin, and RNase7 (1, 2). Some AMPs, such as the human cathelicidin peptide LL-37, are upregulated during inflammation in skin (1). Various microbes colonize the hair follicular canal, and various AMPs may modulate their population and composition (3, 4). It is not known whether the hair shaft per se contains functionally active antimicrobials.
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spelling ntu-10356/879242020-11-01T05:27:43Z Identification of antibacterial components in human hair shafts Subbaiah, Roopa S. Kerk, Swat Kim Lian, Yilong Lunny, Declan Sze, Siu Kwan Ng, Kee Woei Schmidtchen, Artur Adav, Sunil Shankar School of Materials Science & Engineering School of Biological Sciences Interdisciplinary Graduate School (IGS) Lee Kong Chian School of Medicine (LKCMedicine) Nanyang Environment and Water Research Institute DRNTU::Science::Biological sciences Antimicrobial Peptides (AMPs) Human Hair Shafts Antimicrobial peptides (AMPs) are evolutionarily old components of innate immunity. AMPs identified in human skin include defensins, cathelicidin, dermcidin, psoriasin, and RNase7 (1, 2). Some AMPs, such as the human cathelicidin peptide LL-37, are upregulated during inflammation in skin (1). Various microbes colonize the hair follicular canal, and various AMPs may modulate their population and composition (3, 4). It is not known whether the hair shaft per se contains functionally active antimicrobials. MOE (Min. of Education, S’pore) Published version 2018-08-17T07:35:18Z 2019-12-06T16:52:14Z 2018-08-17T07:35:18Z 2019-12-06T16:52:14Z 2018 Journal Article Subbaiah, R. S., Kerk, S. K., Lian, Y., Lunny, D., Sze, S. K., Ng, K. W., et al. (2018). Identification of antibacterial components in human hair shafts. Acta Dermato Venereologica, 98(7), 708-710. 0001-5555 https://hdl.handle.net/10356/87924 http://hdl.handle.net/10220/45603 10.2340/00015555-2952 en Acta Dermato Venereologica © 2018 Acta Dermato-Venereologica. This is an open access article under the CC BY-NC license. www.medicaljournals.se/acta 21 p. application/pdf
spellingShingle DRNTU::Science::Biological sciences
Antimicrobial Peptides (AMPs)
Human Hair Shafts
Subbaiah, Roopa S.
Kerk, Swat Kim
Lian, Yilong
Lunny, Declan
Sze, Siu Kwan
Ng, Kee Woei
Schmidtchen, Artur
Adav, Sunil Shankar
Identification of antibacterial components in human hair shafts
title Identification of antibacterial components in human hair shafts
title_full Identification of antibacterial components in human hair shafts
title_fullStr Identification of antibacterial components in human hair shafts
title_full_unstemmed Identification of antibacterial components in human hair shafts
title_short Identification of antibacterial components in human hair shafts
title_sort identification of antibacterial components in human hair shafts
topic DRNTU::Science::Biological sciences
Antimicrobial Peptides (AMPs)
Human Hair Shafts
url https://hdl.handle.net/10356/87924
http://hdl.handle.net/10220/45603
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