Calcium-dependent and synapsin-dependent pathways for the presynaptic actions of BDNF

Calcium-dependent and synapsin-dependent pathways for the presynaptic actions of BDNF

We used cultured hippocampal neurons to determine the signaling pathways mediating brain-derived neurotrophic factor (BDNF) regulation of spontaneous glutamate and GABA release. BDNF treatment elevated calcium concentration in presynaptic terminals; this calcium signal reached a peak within 1 min an...

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Bibliographic Details
Main Authors: Cheng, Qing, Song, Sang-Ho, Augustine, George James
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2018
Subjects:
Neurotrophins
Synapsins
DRNTU::Science::Medicine
Online Access:https://hdl.handle.net/10356/88507
http://hdl.handle.net/10220/45823

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