Super-contrast photoacoustic resonance imaging
In this paper, a new imaging modality, named photoacoustic resonance imaging (PARI), is proposed and experimentally demonstrated. Being distinct from conventional single nanosecond laser pulse induced wideband PA signal, the proposed PARI method utilizes multi-burst modulated laser source to induce...
| Main Authors: | , , , , |
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| Format: | Journal Article |
| Language: | English |
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2018
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| Online Access: | https://hdl.handle.net/10356/88806 http://hdl.handle.net/10220/45933 |
| _version_ | 1811686393398689792 |
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| author | Gao, Fei Zhang, Ruochong Feng, Xiaohua Liu, Siyu Zheng, Yuanjin |
| author2 | Oraevsky, Alexander A. |
| author_facet | Oraevsky, Alexander A. Gao, Fei Zhang, Ruochong Feng, Xiaohua Liu, Siyu Zheng, Yuanjin |
| author_sort | Gao, Fei |
| collection | NTU |
| description | In this paper, a new imaging modality, named photoacoustic resonance imaging (PARI), is proposed and experimentally demonstrated. Being distinct from conventional single nanosecond laser pulse induced wideband PA signal, the proposed PARI method utilizes multi-burst modulated laser source to induce PA resonant signal with enhanced signal strength and narrower bandwidth. Moreover, imaging contrast could be clearly improved than conventional single-pulse laser based PA imaging by selecting optimum modulation frequency of the laser source, which originates from physical properties of different materials beyond the optical absorption coefficient. Specifically, the imaging steps is as follows: 1: Perform conventional PA imaging by modulating the laser source as a short pulse to identify the location of the target and the background. 2: Shine modulated laser beam on the background and target respectively to characterize their individual resonance frequency by sweeping the modulation frequency of the CW laser source. 3: Select the resonance frequency of the target as the modulation frequency of the laser source, perform imaging and get the first PARI image. Then choose the resonance frequency of the background as the modulation frequency of the laser source, perform imaging and get the second PARI image. 4: subtract the first PARI image from the second PARI image, then we get the contrast-enhanced PARI results over the conventional PA imaging in step 1. Experimental validation on phantoms have been performed to show the merits of the proposed PARI method with much improved image contrast. |
| first_indexed | 2024-10-01T04:59:42Z |
| format | Journal Article |
| id | ntu-10356/88806 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T04:59:42Z |
| publishDate | 2018 |
| record_format | dspace |
| spelling | ntu-10356/888062020-03-07T14:02:37Z Super-contrast photoacoustic resonance imaging Gao, Fei Zhang, Ruochong Feng, Xiaohua Liu, Siyu Zheng, Yuanjin Oraevsky, Alexander A. Wang, Lihong V. School of Electrical and Electronic Engineering Photons Plus Ultrasound: Imaging and Sensing 2018 DRNTU::Engineering::Electrical and electronic engineering Photoacoustic Spectroscopy Modulation In this paper, a new imaging modality, named photoacoustic resonance imaging (PARI), is proposed and experimentally demonstrated. Being distinct from conventional single nanosecond laser pulse induced wideband PA signal, the proposed PARI method utilizes multi-burst modulated laser source to induce PA resonant signal with enhanced signal strength and narrower bandwidth. Moreover, imaging contrast could be clearly improved than conventional single-pulse laser based PA imaging by selecting optimum modulation frequency of the laser source, which originates from physical properties of different materials beyond the optical absorption coefficient. Specifically, the imaging steps is as follows: 1: Perform conventional PA imaging by modulating the laser source as a short pulse to identify the location of the target and the background. 2: Shine modulated laser beam on the background and target respectively to characterize their individual resonance frequency by sweeping the modulation frequency of the CW laser source. 3: Select the resonance frequency of the target as the modulation frequency of the laser source, perform imaging and get the first PARI image. Then choose the resonance frequency of the background as the modulation frequency of the laser source, perform imaging and get the second PARI image. 4: subtract the first PARI image from the second PARI image, then we get the contrast-enhanced PARI results over the conventional PA imaging in step 1. Experimental validation on phantoms have been performed to show the merits of the proposed PARI method with much improved image contrast. Published version 2018-09-11T04:13:16Z 2019-12-06T17:11:14Z 2018-09-11T04:13:16Z 2019-12-06T17:11:14Z 2018 Journal Article Gao, F., Zhang, R., Feng, X., Liu, S., & Zheng, Y. (2018). Super-contrast photoacoustic resonance imaging. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 10494, 104943W-. doi:10.1117/12.2292635 https://hdl.handle.net/10356/88806 http://hdl.handle.net/10220/45933 10.1117/12.2292635 en Progress in Biomedical Optics and Imaging - Proceedings of SPIE © 2018 Society of Photo-optical Instrumentation Engineers (SPIE). This paper was published in Progress in Biomedical Optics and Imaging - Proceedings of SPIE and is made available as an electronic reprint (preprint) with permission of Society of Photo-optical Instrumentation Engineers (SPIE). The published version is available at: [http://dx.doi.org/10.1117/12.2292635]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. 8 p. application/pdf |
| spellingShingle | DRNTU::Engineering::Electrical and electronic engineering Photoacoustic Spectroscopy Modulation Gao, Fei Zhang, Ruochong Feng, Xiaohua Liu, Siyu Zheng, Yuanjin Super-contrast photoacoustic resonance imaging |
| title | Super-contrast photoacoustic resonance imaging |
| title_full | Super-contrast photoacoustic resonance imaging |
| title_fullStr | Super-contrast photoacoustic resonance imaging |
| title_full_unstemmed | Super-contrast photoacoustic resonance imaging |
| title_short | Super-contrast photoacoustic resonance imaging |
| title_sort | super contrast photoacoustic resonance imaging |
| topic | DRNTU::Engineering::Electrical and electronic engineering Photoacoustic Spectroscopy Modulation |
| url | https://hdl.handle.net/10356/88806 http://hdl.handle.net/10220/45933 |
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