Quantitative evaluation of stone fragments in extracorporeal shock wave lithotripsy using a time reversal operator
Extracorporeal shock wave lithotripsy (ESWL) has been used widely in the noninvasive treatment of kidney calculi. The fine fragments less than 2 mm in size can be discharged by urination, which determines the success of ESWL. Although ultrasonic and fluorescent imaging are used to localize the calcu...
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| Format: | Journal Article |
| Language: | English |
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2018
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| Online Access: | https://hdl.handle.net/10356/89298 http://hdl.handle.net/10220/46163 |
| _version_ | 1824455667198459904 |
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| author | Wang, Jen-Chieh Zhou, Yufeng |
| author2 | School of Mechanical and Aerospace Engineering |
| author_facet | School of Mechanical and Aerospace Engineering Wang, Jen-Chieh Zhou, Yufeng |
| author_sort | Wang, Jen-Chieh |
| collection | NTU |
| description | Extracorporeal shock wave lithotripsy (ESWL) has been used widely in the noninvasive treatment of kidney calculi. The fine fragments less than 2 mm in size can be discharged by urination, which determines the success of ESWL. Although ultrasonic and fluorescent imaging are used to localize the calculi, it’s challenging to monitor the stone comminution progress, especially at the late stage of ESWL when fragments spread out as a cloud. The lack of real-time and quantitative evaluation makes this procedure semi-blind, resulting in either under- or over-treatment after the legal number of pulses required by FDA. The time reversal operator (TRO) method has the ability to detect point-like scatterers, and the number of non-zero eigenvalues of TRO is equal to that of the scatterers. In this study, the validation of TRO method to identify stones was illustrated from both numerical and experimental results for one to two stones with various sizes and locations. Furthermore, the parameters affecting the performance of TRO method has also been investigated. Overall, TRO method is effective in identifying the fragments in a stone cluster in real-time. Further development of a detection system and evaluation of its performance both in vitro and in vivo during ESWL is necessary for application. |
| first_indexed | 2025-02-19T03:41:51Z |
| format | Journal Article |
| id | ntu-10356/89298 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2025-02-19T03:41:51Z |
| publishDate | 2018 |
| record_format | dspace |
| spelling | ntu-10356/892982023-03-04T17:17:07Z Quantitative evaluation of stone fragments in extracorporeal shock wave lithotripsy using a time reversal operator Wang, Jen-Chieh Zhou, Yufeng School of Mechanical and Aerospace Engineering PROCEEDINGS FROM THE 14TH INTERNATIONAL SYMPOSIUM ON THERAPEUTIC ULTRASOUND Extracorporeal Shock Wave Lithotripsy DRNTU::Engineering::Mechanical engineering Stone Fragments Extracorporeal shock wave lithotripsy (ESWL) has been used widely in the noninvasive treatment of kidney calculi. The fine fragments less than 2 mm in size can be discharged by urination, which determines the success of ESWL. Although ultrasonic and fluorescent imaging are used to localize the calculi, it’s challenging to monitor the stone comminution progress, especially at the late stage of ESWL when fragments spread out as a cloud. The lack of real-time and quantitative evaluation makes this procedure semi-blind, resulting in either under- or over-treatment after the legal number of pulses required by FDA. The time reversal operator (TRO) method has the ability to detect point-like scatterers, and the number of non-zero eigenvalues of TRO is equal to that of the scatterers. In this study, the validation of TRO method to identify stones was illustrated from both numerical and experimental results for one to two stones with various sizes and locations. Furthermore, the parameters affecting the performance of TRO method has also been investigated. Overall, TRO method is effective in identifying the fragments in a stone cluster in real-time. Further development of a detection system and evaluation of its performance both in vitro and in vivo during ESWL is necessary for application. Published version 2018-10-02T02:51:18Z 2019-12-06T17:22:18Z 2018-10-02T02:51:18Z 2019-12-06T17:22:18Z 2017 Journal Article Wang, J.-C., & Zhou, Y. (2017). Quantitative evaluation of stone fragments in extracorporeal shock wave lithotripsy using a time reversal operator. AIP Conference Proceedings, 1821, 150004-. doi:10.1063/1.4977648 0094-243X https://hdl.handle.net/10356/89298 http://hdl.handle.net/10220/46163 10.1063/1.4977648 en AIP Conference Proceedings ©The Author(s) (Published by AIP Publishing). This paper was published in AIP Conference Proceedings and is made available as an electronic reprint (preprint) with permission of the author(s) (Published by AIP Publishing). The published version is available at: [http://dx.doi.org/10.1063/1.4977648]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. 5 p. application/pdf |
| spellingShingle | Extracorporeal Shock Wave Lithotripsy DRNTU::Engineering::Mechanical engineering Stone Fragments Wang, Jen-Chieh Zhou, Yufeng Quantitative evaluation of stone fragments in extracorporeal shock wave lithotripsy using a time reversal operator |
| title | Quantitative evaluation of stone fragments in extracorporeal shock wave lithotripsy using a time reversal operator |
| title_full | Quantitative evaluation of stone fragments in extracorporeal shock wave lithotripsy using a time reversal operator |
| title_fullStr | Quantitative evaluation of stone fragments in extracorporeal shock wave lithotripsy using a time reversal operator |
| title_full_unstemmed | Quantitative evaluation of stone fragments in extracorporeal shock wave lithotripsy using a time reversal operator |
| title_short | Quantitative evaluation of stone fragments in extracorporeal shock wave lithotripsy using a time reversal operator |
| title_sort | quantitative evaluation of stone fragments in extracorporeal shock wave lithotripsy using a time reversal operator |
| topic | Extracorporeal Shock Wave Lithotripsy DRNTU::Engineering::Mechanical engineering Stone Fragments |
| url | https://hdl.handle.net/10356/89298 http://hdl.handle.net/10220/46163 |
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