Towards a clinical implementation of μOCT instrument for in vivo imaging of human airways
High resolution micro-optical coherence tomography (µOCT) technology has been demonstrated to be useful for imaging respiratory epithelial functional microanatomy relevant to the study of pulmonary diseases such as cystic fibrosis and COPD. We previously reported the use of a benchtop μOCT imaging t...
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Format: | Conference Paper |
Language: | English |
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2018
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Online Access: | https://hdl.handle.net/10356/89458 http://hdl.handle.net/10220/44956 |
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author | Leung, Hui Min Cui, Dongyao Ford, Timothy N. Hyun, Daryl Dong, Jing Yin, Biwei Birket, Susan E. Solomon, George M. Liu, Linbo Rowe, Steven M. Tearney, Guillermo J. |
author2 | Raghavachari, Ramesh |
author_facet | Raghavachari, Ramesh Leung, Hui Min Cui, Dongyao Ford, Timothy N. Hyun, Daryl Dong, Jing Yin, Biwei Birket, Susan E. Solomon, George M. Liu, Linbo Rowe, Steven M. Tearney, Guillermo J. |
author_sort | Leung, Hui Min |
collection | NTU |
description | High resolution micro-optical coherence tomography (µOCT) technology has been demonstrated to be useful for imaging respiratory epithelial functional microanatomy relevant to the study of pulmonary diseases such as cystic fibrosis and COPD. We previously reported the use of a benchtop μOCT imaging technology to image several relevant respiratory epithelial functional microanatomy at 40 fps and at lateral and axial resolutions of 2 and 1.3μm, respectively. We now present the development of a portable μOCT imaging system with comparable optical and imaging performance, which enables the μOCT technology to be translated to the clinic for in vivo imaging of human airways. |
first_indexed | 2024-10-01T03:10:40Z |
format | Conference Paper |
id | ntu-10356/89458 |
institution | Nanyang Technological University |
language | English |
last_indexed | 2024-10-01T03:10:40Z |
publishDate | 2018 |
record_format | dspace |
spelling | ntu-10356/894582020-03-07T13:24:46Z Towards a clinical implementation of μOCT instrument for in vivo imaging of human airways Leung, Hui Min Cui, Dongyao Ford, Timothy N. Hyun, Daryl Dong, Jing Yin, Biwei Birket, Susan E. Solomon, George M. Liu, Linbo Rowe, Steven M. Tearney, Guillermo J. Raghavachari, Ramesh Liang, Rongguang Pfefer, T. Joshua School of Electrical and Electronic Engineering Proceeding of SPIE 10056, Design and Quality for Biomedical Technologies X Centre for OptoElectronics and Biophotonics Cystic Fibrosis Imaging Techniques High resolution micro-optical coherence tomography (µOCT) technology has been demonstrated to be useful for imaging respiratory epithelial functional microanatomy relevant to the study of pulmonary diseases such as cystic fibrosis and COPD. We previously reported the use of a benchtop μOCT imaging technology to image several relevant respiratory epithelial functional microanatomy at 40 fps and at lateral and axial resolutions of 2 and 1.3μm, respectively. We now present the development of a portable μOCT imaging system with comparable optical and imaging performance, which enables the μOCT technology to be translated to the clinic for in vivo imaging of human airways. Published version 2018-06-05T08:27:52Z 2019-12-06T17:25:58Z 2018-06-05T08:27:52Z 2019-12-06T17:25:58Z 2017 Conference Paper Leung, H. M., Cui, D., Ford, T. N., Hyun, D., Dong, J., Yin, B., et al. (2017). Towards a clinical implementation of μOCT instrument for in vivo imaging of human airways. Proceeding of SPIE 10056, Design and Quality for Biomedical Technologies X, 1005614-. https://hdl.handle.net/10356/89458 http://hdl.handle.net/10220/44956 10.1117/12.2253423 en © 2017 Society of Photo-optical Instrumentation Engineers (SPIE). This paper was published in Proceeding of SPIE 10056, Design and Quality for Biomedical Technologies X and is made available as an electronic reprint (preprint) with permission of SPIE. The published version is available at: [http://dx.doi.org/10.1117/12.2253423]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. 1 p. application/pdf |
spellingShingle | Cystic Fibrosis Imaging Techniques Leung, Hui Min Cui, Dongyao Ford, Timothy N. Hyun, Daryl Dong, Jing Yin, Biwei Birket, Susan E. Solomon, George M. Liu, Linbo Rowe, Steven M. Tearney, Guillermo J. Towards a clinical implementation of μOCT instrument for in vivo imaging of human airways |
title | Towards a clinical implementation of μOCT instrument for in vivo imaging of human airways |
title_full | Towards a clinical implementation of μOCT instrument for in vivo imaging of human airways |
title_fullStr | Towards a clinical implementation of μOCT instrument for in vivo imaging of human airways |
title_full_unstemmed | Towards a clinical implementation of μOCT instrument for in vivo imaging of human airways |
title_short | Towards a clinical implementation of μOCT instrument for in vivo imaging of human airways |
title_sort | towards a clinical implementation of μoct instrument for in vivo imaging of human airways |
topic | Cystic Fibrosis Imaging Techniques |
url | https://hdl.handle.net/10356/89458 http://hdl.handle.net/10220/44956 |
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