Label-free alignment of nonmagnetic particles in a small uniform magnetic field

Label-free manipulation of biological entities can minimize damage, increase viability and improve efficiency of subsequent analysis. Understanding the mechanism of interaction between magnetic and nonmagnetic particles in an inverse ferrofluid can provide a mechanism of label-free manipulation of s...

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Main Authors: Wang, Zhaomeng, Wang, Ying, Wu, Rui Ge, Wang, Z. P, Ramanujan, Raju V
Other Authors: School of Materials Science & Engineering
Format: Journal Article
Language:English
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10356/89849
http://hdl.handle.net/10220/48255
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author Wang, Zhaomeng
Wang, Ying
Wu, Rui Ge
Wang, Z. P
Ramanujan, Raju V
author2 School of Materials Science & Engineering
author_facet School of Materials Science & Engineering
Wang, Zhaomeng
Wang, Ying
Wu, Rui Ge
Wang, Z. P
Ramanujan, Raju V
author_sort Wang, Zhaomeng
collection NTU
description Label-free manipulation of biological entities can minimize damage, increase viability and improve efficiency of subsequent analysis. Understanding the mechanism of interaction between magnetic and nonmagnetic particles in an inverse ferrofluid can provide a mechanism of label-free manipulation of such entities in a uniform magnetic field. The magnetic force, induced by relative magnetic susceptibility difference between nonmagnetic particles and surrounding magnetic particles as well as particle–particle interaction were studied. Label-free alignment of nonmagnetic particles can be achieved by higher magnetic field strength (Ba ), smaller particle spacing (R), larger particle size (rp1 ), and higher relative magnetic permeability difference between particle and the surrounding fluid (Rμr ). Rμr can be used to predict the direction of the magnetic force between both magnetic and nonmagnetic particles. A sandwich structure, containing alternate layers of magnetic and nonmagnetic particle chains, was studied. This work can be used for manipulation of nonmagnetic particles in lab-on-a-chip applications.
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spelling ntu-10356/898492020-06-01T10:13:50Z Label-free alignment of nonmagnetic particles in a small uniform magnetic field Wang, Zhaomeng Wang, Ying Wu, Rui Ge Wang, Z. P Ramanujan, Raju V School of Materials Science & Engineering DRNTU::Engineering::Materials Magnetic Forces Magnetic Particles Label-free manipulation of biological entities can minimize damage, increase viability and improve efficiency of subsequent analysis. Understanding the mechanism of interaction between magnetic and nonmagnetic particles in an inverse ferrofluid can provide a mechanism of label-free manipulation of such entities in a uniform magnetic field. The magnetic force, induced by relative magnetic susceptibility difference between nonmagnetic particles and surrounding magnetic particles as well as particle–particle interaction were studied. Label-free alignment of nonmagnetic particles can be achieved by higher magnetic field strength (Ba ), smaller particle spacing (R), larger particle size (rp1 ), and higher relative magnetic permeability difference between particle and the surrounding fluid (Rμr ). Rμr can be used to predict the direction of the magnetic force between both magnetic and nonmagnetic particles. A sandwich structure, containing alternate layers of magnetic and nonmagnetic particle chains, was studied. This work can be used for manipulation of nonmagnetic particles in lab-on-a-chip applications. 2019-05-17T05:19:54Z 2019-12-06T17:34:59Z 2019-05-17T05:19:54Z 2019-12-06T17:34:59Z 2018 Journal Article Wang, Z., Wang, Y., Wu, R. G., Wang, Z. P., & Ramanujan, R. V. (2018). Label-free alignment of nonmagnetic particles in a small uniform magnetic field. Journal of Nanoscience and Nanotechnology, 18(1), 634-644. doi:10.1166/jnn.2018.14704 1533-4880 https://hdl.handle.net/10356/89849 http://hdl.handle.net/10220/48255 10.1166/jnn.2018.14704 en Journal of Nanoscience and Nanotechnology © 2018 American Scientific Publishers. All rights reserved.
spellingShingle DRNTU::Engineering::Materials
Magnetic Forces
Magnetic Particles
Wang, Zhaomeng
Wang, Ying
Wu, Rui Ge
Wang, Z. P
Ramanujan, Raju V
Label-free alignment of nonmagnetic particles in a small uniform magnetic field
title Label-free alignment of nonmagnetic particles in a small uniform magnetic field
title_full Label-free alignment of nonmagnetic particles in a small uniform magnetic field
title_fullStr Label-free alignment of nonmagnetic particles in a small uniform magnetic field
title_full_unstemmed Label-free alignment of nonmagnetic particles in a small uniform magnetic field
title_short Label-free alignment of nonmagnetic particles in a small uniform magnetic field
title_sort label free alignment of nonmagnetic particles in a small uniform magnetic field
topic DRNTU::Engineering::Materials
Magnetic Forces
Magnetic Particles
url https://hdl.handle.net/10356/89849
http://hdl.handle.net/10220/48255
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