Polymersome nanoreactors for enzymatic ring-opening polymerization
Polystyrene-polyisocyanopeptide (PS-PIAT) polymersomes containing CALB in two different locations, one in the aqueous inner compartment and one in the bilayer, were investigated for enzymatic ring-opening polymerization...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/91181 http://hdl.handle.net/10220/7050 |
| Summary: | Polystyrene-polyisocyanopeptide (PS-PIAT) polymersomes containing CALB in two different locations, one in
the aqueous inner compartment and one in the bilayer, were investigated for enzymatic ring-opening polymerization
of lactones in water. It is shown that the monomers 8-octanolactone and dodecalactone yield oligomers with this
polymersome system. It is also observed that the polymerization activity is dependent on the position of the
enzyme in the polymersome. SEM investigations show that the polymersome structures were destabilized during
the polymerization. Further investigations show that the vesicular morphology of the polymersomes was destabilized
only in the case of polymer product formation. |
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