Polymersome nanoreactors for enzymatic ring-opening polymerization
Polystyrene-polyisocyanopeptide (PS-PIAT) polymersomes containing CALB in two different locations, one in the aqueous inner compartment and one in the bilayer, were investigated for enzymatic ring-opening polymerization...
| Main Authors: | , , , , , |
|---|---|
| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2011
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/91181 http://hdl.handle.net/10220/7050 |
| _version_ | 1826122877447962624 |
|---|---|
| author | De Hoog, Hans-Peter M. Cornelissen, Jeroen J. L. M. Nallani, Madhavan Palmans, Anja R. A. Van Hest, Jan C. M. Nolte, Roeland J. M. |
| author2 | School of Materials Science & Engineering |
| author_facet | School of Materials Science & Engineering De Hoog, Hans-Peter M. Cornelissen, Jeroen J. L. M. Nallani, Madhavan Palmans, Anja R. A. Van Hest, Jan C. M. Nolte, Roeland J. M. |
| author_sort | De Hoog, Hans-Peter M. |
| collection | NTU |
| description | Polystyrene-polyisocyanopeptide (PS-PIAT) polymersomes containing CALB in two different locations, one in
the aqueous inner compartment and one in the bilayer, were investigated for enzymatic ring-opening polymerization
of lactones in water. It is shown that the monomers 8-octanolactone and dodecalactone yield oligomers with this
polymersome system. It is also observed that the polymerization activity is dependent on the position of the
enzyme in the polymersome. SEM investigations show that the polymersome structures were destabilized during
the polymerization. Further investigations show that the vesicular morphology of the polymersomes was destabilized
only in the case of polymer product formation. |
| first_indexed | 2024-10-01T05:55:26Z |
| format | Journal Article |
| id | ntu-10356/91181 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:55:26Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | ntu-10356/911812020-06-01T10:21:18Z Polymersome nanoreactors for enzymatic ring-opening polymerization De Hoog, Hans-Peter M. Cornelissen, Jeroen J. L. M. Nallani, Madhavan Palmans, Anja R. A. Van Hest, Jan C. M. Nolte, Roeland J. M. School of Materials Science & Engineering DRNTU::Engineering::Materials::Biomaterials Polystyrene-polyisocyanopeptide (PS-PIAT) polymersomes containing CALB in two different locations, one in the aqueous inner compartment and one in the bilayer, were investigated for enzymatic ring-opening polymerization of lactones in water. It is shown that the monomers 8-octanolactone and dodecalactone yield oligomers with this polymersome system. It is also observed that the polymerization activity is dependent on the position of the enzyme in the polymersome. SEM investigations show that the polymersome structures were destabilized during the polymerization. Further investigations show that the vesicular morphology of the polymersomes was destabilized only in the case of polymer product formation. None of the above 2011-09-14T07:44:50Z 2019-12-06T18:01:08Z 2011-09-14T07:44:50Z 2019-12-06T18:01:08Z 2007 2007 Journal Article Nallani, M., de Hoog, H. P. M., Cornelissen, J. J. L. M., Palmans, A. R. A., van Hest, J. C. M., & Nolte, R. J. M. (2007). Polymersome Nanoreactors for Enzymatic Ring-Opening Polymerization. Biomacromolecules, 8(12), 3723-3728. 1525-7797 https://hdl.handle.net/10356/91181 http://hdl.handle.net/10220/7050 10.1021/bm7005938 155290 en Biomacromolecules © 2007 American Chemical Society 6 p. |
| spellingShingle | DRNTU::Engineering::Materials::Biomaterials De Hoog, Hans-Peter M. Cornelissen, Jeroen J. L. M. Nallani, Madhavan Palmans, Anja R. A. Van Hest, Jan C. M. Nolte, Roeland J. M. Polymersome nanoreactors for enzymatic ring-opening polymerization |
| title | Polymersome nanoreactors for enzymatic ring-opening polymerization |
| title_full | Polymersome nanoreactors for enzymatic ring-opening polymerization |
| title_fullStr | Polymersome nanoreactors for enzymatic ring-opening polymerization |
| title_full_unstemmed | Polymersome nanoreactors for enzymatic ring-opening polymerization |
| title_short | Polymersome nanoreactors for enzymatic ring-opening polymerization |
| title_sort | polymersome nanoreactors for enzymatic ring opening polymerization |
| topic | DRNTU::Engineering::Materials::Biomaterials |
| url | https://hdl.handle.net/10356/91181 http://hdl.handle.net/10220/7050 |
| work_keys_str_mv | AT dehooghanspeterm polymersomenanoreactorsforenzymaticringopeningpolymerization AT cornelissenjeroenjlm polymersomenanoreactorsforenzymaticringopeningpolymerization AT nallanimadhavan polymersomenanoreactorsforenzymaticringopeningpolymerization AT palmansanjara polymersomenanoreactorsforenzymaticringopeningpolymerization AT vanhestjancm polymersomenanoreactorsforenzymaticringopeningpolymerization AT nolteroelandjm polymersomenanoreactorsforenzymaticringopeningpolymerization |